FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\GirdinGFP
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General Information
Symbol
Dmel\GirdinGFP
Species
D. melanogaster
Name
FlyBase ID
FBal0319532
Feature type
allele
Associated gene
Dmel\Girdin
Associated Insertion(s)
Carried in Construct
P{Girdin-GFP}
Key Links
Transgenic product class
genomic_DNA
(Ha et al., 2015)
wild_type
(Ha et al., 2015)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Ha et al., 2015)
wild_type
(Ha et al., 2015)
Mutagen
in vitro construct
(Ha et al., 2015)
Progenitor genotype
Carried in construct
P{Girdin-GFP}
Cytology
Description

Genomic fragment containing the Girdin gene and endogenous promoter. The open reading frame is tagged at the C-terminal end with GFP.

(Ha et al., 2015)
Allele components
Component
Use(s)
Regulatory region(s)
Girdin
Encoded product / tool
Girdin
Tagged with
GFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      epitope tag
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      pupal stage P6 -- pharate adult stage P14
      epithelial cell of thorax
      (Ha et al., 2015)
      mechanosensory sensory organ
      (Ha et al., 2015)
      mechanosensory neuron
      (Ha et al., 2015)
      scolopidial cilium
      (Ha et al., 2015)
      spermatozoon
      (Ha et al., 2015)
      Additional Information
      Statement
      Reference

      Girdin-GFP is observed from 30 hr APF in mechanosensory organs. It localizes to the dendritic tip in three foci described as a loop, a tube, and a cap structure. The tube staining is at the distal tip of the inner segment and the cap-like and loop-like structures localize at or around the cilium. It is also observed in the membrane of thoracic epithelial cells and in the cytoplasm of sperm cells.

      (Ha et al., 2015)
       
      Marker for
      Reflects expression of
      Girdin
      (Ha et al., 2015)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      GirdinGFP rescues Girdin101

      (Ha et al., 2015)
      Comments

      GirdinT:Avic\GFP rescues behavioral phenotypes and sensory neuron dendrite degeneration, and generates viable Girdin101 flies.

      (Ha et al., 2015)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      GirdinGFP
      GirdinT:Avic\GFP
      Name Synonyms
      Secondary FlyBase IDs
        References (1)