FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Adcy1UAS.cUa
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General Information
Symbol
Dmel\Adcy1UAS.cUa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Unknown
FlyBase ID
FBal0319546
Feature type
allele
Associated gene
Dmel\Adcy1
Associated Insertion(s)
Carried in Construct
P{UAS-Adcy1.U}
Also Known As
UAS-rut
Key Links
Transgenic product class
wild_type
(FlyBase Curators, 2025-)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(FlyBase Curators, 2025-)
Mutagen
in vitro construct
(FlyBase Curators, 2025-)
Progenitor genotype
Carried in construct
P{UAS-Adcy1.U}
Cytology
Description

UAS regulatory sequences drive expression of Adcy1.

(FlyBase Curators, 2025-)

FlyBase curator comment: this entry represents a transgenic construct where the particular construct used cannot be determined.

(FlyBase Curators, 2025-)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Adcy1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  intellectual disability
      modeled by chico1
      (Naganos et al., 2016)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Ectopic expression of rutScer\UAS.cUa under the control of Scer\GAL4ey-OK107 does not alter performance of adult flies in a behavioral olfactory learning assay compared to controls, either under standard training conditions or after short duration training.

      (Naganos et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      NOT Suppressor of
      Statement
      Reference

      Scer\GAL4ey-OK107/Adcy1UAS.cUa is a non-suppressor of abnormal neuroanatomy phenotype of chico1

      (Naganos et al., 2016)
      Phenotype Manifest In
      NOT Suppressor of
      Statement
      Reference

      Scer\GAL4ey-OK107/Adcy1UAS.cUa is a non-suppressor of Kenyon cell phenotype of chico1

      (Naganos et al., 2016)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The decreased learning index in a behavioral olfactory learning assay (measuring 3 min memory) observed in chico1 mutant adults is restored to wild-type level by expression of rutScer\UAS.cUa under the control of Scer\GAL4ey-OK107 and significantly increased by expression under the Scer\GAL4Mef2.247.Switch driver in animals fed RU486 (to activate expression) compared to controls.

      The decreased number of Kenyon cells seen in chico1 homozygote brains cannot be restored by expression of rutScer\UAS.cUa under the control of Scer\GAL4ey-OK107 in the mutant background.

      (Naganos et al., 2016)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      Adcy1UAS.cUa
      rutScer\UAS.cUa
      rutUAS.cUa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Unknown
      Secondary FlyBase IDs
        References (4)