FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\DriceL2
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General Information
Symbol
Dmel\DriceL2
Species
D. melanogaster
Name
FlyBase ID
FBal0319653
Feature type
allele
Associated gene
Dmel\Drice
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Wu et al., 2016)
Mutagen
ethyl methanesulfonate
(Wu et al., 2016)
Progenitor genotype
Cytology
Description

Revision of data reported in FBrf0231218.

(Wu and Bergmann, 2016.9.7)

Amino acid replacement: G94E.

(Wu and Bergmann, 2016.9.7)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3R:29,800,178..29,800,178 [+]
Nucleotide change:

G29800178A

Reported nucleotide change:

G?A

Amino acid change:

G94E | Drice-PA

Reported amino acid change:

G94E

(Wu and Bergmann, 2016.9.7)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      DriceL2/DriceL2 flies are viable and have wing clearance defects (similar to those seen in Drice17 or DriceΔ1).

      (Wu et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      DriceL2/Drice17 is a suppressor of visible phenotype of hidGMR.PG

      (Wu et al., 2016)

      DriceΔ1/DriceL2 is a suppressor of visible phenotype of rprGMR.PW

      (Wu et al., 2016)

      Drice[+]/DriceL2 is a suppressor of visible phenotype of rprGMR.PW

      (Wu et al., 2016)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      DriceL2/Drice17 is a suppressor of eye phenotype of hidGMR.PG

      (Wu et al., 2016)

      DriceΔ1/DriceL2 is a suppressor of eye phenotype of rprGMR.PW

      (Wu et al., 2016)

      Drice[+]/DriceL2 is a suppressor of eye phenotype of rprGMR.PW

      (Wu et al., 2016)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Drice17/DriceL2 (but not Drice17/+) significantly suppresses the eye ablation phenotype in hidGMR.PG flies. DriceΔ1/DriceL2 (but not DriceΔ1/+) significantly suppresses the eye ablation phenotype in rprGMR.PW flies. DriceL2/+ weakly suppresses the eye ablation phenotype in rprGMR.PW flies.

      (Wu et al., 2016)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      DriceL2
      drICEL2
      (Wu et al., 2016)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)