FB2026_02 , released June 18, 2026
Allele: Dmel\Otenanos.PB
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General Information
Symbol
Dmel\Otenanos.PB
Species
D. melanogaster
Name
nanos promoter construct of Barton
FlyBase ID
FBal0319976
Feature type
allele
Associated gene
Dmel\Ote
Associated Insertion(s)
Carried in Construct
P{nanos-Ote.B}
Key Links
Transgenic product class
wild_type
(Barton et al., 2016)
Mutagen
    Nature of the Allele
    Transgenic product class
    wild_type
    (Barton et al., 2016)
    Mutagen
    Progenitor genotype
    Carried in construct
    P{nanos-Ote.B}
    Cytology
    Description

    A 445bp fragment containing nos promoter and 5'UTR sequence (-184 to +261) is fused upstream of the Ote gene (+98 to +1477).

    (Barton et al., 2016)
    Allele components
    Component
    Use(s)
    Regulatory region(s)
    nanos
    Encoded product / tool
    Ote
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Partially rescues

        Otenanos.PB partially rescues OtePK/OteB279

        (Barton et al., 2016)
        Comments

        Expression of Otenos.PB restores fertility, rescues the germline stem cell maintenance, differentiation germ cell number, somatic cell number and cell adhesion phenotypes of both OtePK/OteB279 mutant males and females, but does not fully restore hub size in mutant males.

        (Barton et al., 2016)
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (3)
        Reported As
        Symbol Synonym
        Otenanos.PB
        Otenos.PB
        Name Synonyms
        nanos promoter construct of Barton
        Secondary FlyBase IDs
          References (2)