FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\TrehMI05512+s2
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General Information
Symbol
Dmel\TrehMI05512+s2
Species
D. melanogaster
Name
FlyBase ID
FBal0321692
Feature type
allele
Associated gene
Dmel\Treh
Associated Insertion(s)
Mi{MIC}MI05512
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
CRISPR/Cas9
(Yoshida et al., 2016)
Progenitor genotype
Mi{MIC}MI05512
(Yoshida et al., 2016)
Associated Insertion(s)
Mi{MIC}MI05512
Cytology
Description

Frameshift insertion of 1bp within the signal peptide sequence present in secreted isoforms of Treh. The Mi{MIC}TrehMI05512 insertion is also still present.

(Yoshida et al., 2016)
Allele components
Component
Use(s)
Inserted element
Mi{MIC}
Also carries
attP
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      TrehMI05512+s2/TrehMI05512+s2 mutants exhibit lethality during pupal stage.

      (Yoshida et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      TrehMI05512+s2
      TrehMIC+s2
      (Yoshida et al., 2016)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)