FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Tm1eg1
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General Information
Symbol
Dmel\Tm1eg1
Species
D. melanogaster
Name
FlyBase ID
FBal0325534
Feature type
allele
Associated gene
Dmel\Tm1
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Gáspár et al., 2017)
Progenitor genotype
P{lacW}Tm1gs1
(Gáspár et al., 2017)
Cytology
Description

Imprecise excision of P{lacW}Tm1gs1, resulting in a loss of expression of Tm1 isoforms C, H and I in homozygous ovaries.

(Gáspár et al., 2017)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      Tm1eg9/Tm1eg1 has oocyte phenotype, suppressible by Scer\GAL4VP16.osk/Khc401.UASp.Tag:MCP

      (Gáspár et al., 2017)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      Tm1eg9/Tm1eg1 is rescued by Scer\GAL4VP16.osk/Tm1UASp.I.Emerald

      (Gáspár et al., 2017)
      Comments

      Expression of Tm1Scer\UAS.P\T.I.T:Avic\GFP-EMD under the control of Scer\GAL4osk.T:Hsim\VP16 rescues the grandchildless phenotype of Tm1eg9/Tm1eg1 and restores the posterior pole localization of osk mRNA in the mutant oocytes.

      (Gáspár et al., 2017)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Tm1eg1
      (Cassella and Ephrussi, 2022, Gáspár et al., 2017)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)