FB2026_03 , released September 17, 2026
Allele: Dmel\TpnC4δ6
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General Information
Symbol
Dmel\TpnC4δ6
Species
D. melanogaster
Name
FlyBase ID
FBal0325811
Feature type
allele
Associated gene
Dmel\TpnC4
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Chechenova et al., 2017)
Mutagen
CRISPR/Cas9
(Chechenova et al., 2017)
Progenitor genotype
Cytology
Description

Contains two single nucleotide insertions in exon 3 of TpnC4; one of the insertions produces a premature stop codon after amino acid 14 of the polypeptide chain.

(Chechenova et al., 2017)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
insertion
2R:5,506,706..5,506,707 [-]
Inserted_sequence:

T

Comment:

The insertion of a T between the indicated bases causes a frameshift and creates a stop codon (TAG) just after amino acid 14 of TpnC4. The insertion of a T at 2R:5506693 (after the stop codon) was also reported.

(Chechenova and Cripps, 2018.3.13)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      This allele was made in a TpnC41Cδ2 background.

      (Chechenova et al., 2017)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      TpnC4delta#6
      (Chechenova and Cripps, 2018.3.13)
      TpnC4δ#6
      (Chechenova et al., 2017)
      TpnC4δ6
      Name Synonyms
      Secondary FlyBase IDs
        References (2)