FB2026_02 , released June 18, 2026
Allele: Dmel\Nrx-1Δ1760-1813.UAS
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General Information
Symbol
Dmel\Nrx-1Δ1760-1813.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0325863
Feature type
allele
Associated gene
Dmel\Nrx-1
Associated Insertion(s)
Carried in Construct
P{UAS-Nrx-1.Δ1760-1813}
Key Links
Transgenic product class
inframe_deletion
(Liu et al., 2017)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Liu et al., 2017)
Mutagen
in vitro construct
(Liu et al., 2017)
Progenitor genotype
Carried in construct
P{UAS-Nrx-1.Δ1760-1813}
Cytology
Description

UASt regulatory sequences drive expression of Nrx-1 cDNA with a deletion of the Ephrin-binding site (1760-1813).

(Liu et al., 2017)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Nrx-1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      Scer\GAL4GMR31C06/Nrx-1Δ1760-1813.UAS fails to rescue Nrx-1Δ83

      (Liu et al., 2017)
      Comments

      The defective columnar restriction of L4 lamina neuron axons (which frequently invade adjacent medulla columns) observed in Nrx-1Δ83 mutant adults cannot be rescued by expression of Nrx-1Δ1760-1813.Scer\UAS driven by Scer\GAL4GMR31C06.

      (Liu et al., 2017)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Nrx-1Δ1760-1813.Scer\UAS
      Nrx-1Δ1760-1813.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (1)