FlyBase Allele Report: Scer\GAL4[GMR31C06]

General Information

Symbol

Scer\GAL4^GMR31C06

Species

S. cerevisiae

Name

FlyBase ID

FBal0251472

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

Carried in Construct

P{GMR31C06-GAL4}

Also Known As

31C06-Gal4, GMR31C06-GAL4, L4-GAL4, R31C06-GAL4, R31C06

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Pfeiffer et al., 2011.2.9)

Progenitor genotype

Carried in construct

P{GMR31C06-GAL4}

Cytology

Description

A 1938 base pair fragment from the flanking non-coding or intronic region of Ubx is fused upstream of a Drosophila core synthetic promoter (DSCP) that is followed by sequence encoding a GAL4 driver.

(Pfeiffer et al., 2011.2.9)

Allele components

Component

Use(s)

Regulatory region(s)

GMR31C06

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

pupal stage P7 -- pharate adult stage P9

lamina monopolar neuron L4

(Liu et al., 2017)

pharate adult stage P8

lamina monopolar neuron L4

(Trush et al., 2019)

pharate adult stage P9

lamina monopolar neuron L4

Comment: 72h APF

(Astigarraga et al., 2018)

Additional Information

Statement

Reference

ScerGAL4^GMR31C06 drives expression in laminar monopolar neurons L4 at 48 hours APF.

(Trush et al., 2019)

ScerGAL4^GMR31C06 drives expression in L4 neurons after 40 hr APF.

(Liu et al., 2017)

Marker for

lamina monopolar neuron L4

(Astigarraga et al., 2018)

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy | adult stage, with Ephrin^HMS01289

(Liu et al., 2017)

abnormal neuroanatomy | adult stage, with Nrx-1^HMS00403

(Liu et al., 2017)

Phenotype Manifest In

axon | adult stage, with Ephrin^HMS01289

(Liu et al., 2017)

axon | adult stage, with Nrx-1^HMS00403

(Liu et al., 2017)

lamina monopolar neuron L4 | adult stage, with Ephrin^HMS01289

(Liu et al., 2017)

lamina monopolar neuron L4 | adult stage, with Nrx-1^HMS00403

(Liu et al., 2017)

medulla | adult stage, with Ephrin^HMS01289

(Liu et al., 2017)

medulla | adult stage, with Nrx-1^HMS00403

(Liu et al., 2017)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

Ephrin^HMS01289, Scer\GAL4^GMR31C06 has abnormal neuroanatomy | adult stage phenotype, non-enhanceable by Nrx-1²⁷³/Nrx-1^Δ83

(Liu et al., 2017)

Ephrin^HMS01289, Scer\GAL4^GMR31C06 has abnormal neuroanatomy | adult stage phenotype, non-enhanceable by Nlg4^KO10/Nlg4^KO10

(Liu et al., 2017)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

Ephrin^HMS01289, Scer\GAL4^GMR31C06 has lamina monopolar neuron L4 | adult stage phenotype, non-enhanceable by Nrx-1²⁷³/Nrx-1^Δ83

(Liu et al., 2017)

Ephrin^HMS01289, Scer\GAL4^GMR31C06 has axon | adult stage phenotype, non-enhanceable by Nrx-1²⁷³/Nrx-1^Δ83

(Liu et al., 2017)

Ephrin^HMS01289, Scer\GAL4^GMR31C06 has medulla | adult stage phenotype, non-enhanceable by Nrx-1²⁷³/Nrx-1^Δ83

(Liu et al., 2017)

Ephrin^HMS01289, Scer\GAL4^GMR31C06 has lamina monopolar neuron L4 | adult stage phenotype, non-enhanceable by Nlg4^KO10/Nlg4^KO10

(Liu et al., 2017)

Ephrin^HMS01289, Scer\GAL4^GMR31C06 has axon | adult stage phenotype, non-enhanceable by Nlg4^KO10/Nlg4^KO10

(Liu et al., 2017)

Ephrin^HMS01289, Scer\GAL4^GMR31C06 has medulla | adult stage phenotype, non-enhanceable by Nlg4^KO10/Nlg4^KO10

(Liu et al., 2017)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Scer\GAL4^GMR31C06/Nrx-1^UAS.cZa rescues Nrx-1^Δ83

(Liu et al., 2017)

Fails to rescue

Scer\GAL4^GMR31C06/Nrx-1^{Δ1760-1813.UAS} fails to rescue Nrx-1^Δ83

(Liu et al., 2017)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

49883

w¹¹¹⁸; P{GMR31C06-GAL4}attP2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Scer\GAL4^GMR31C06

Name Synonyms

Secondary FlyBase IDs

References (14)

Report Sections

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