FlyBase Allele Report: Dmel\ms(2)05704[05704]

General Information

Symbol

Dmel\ms(2)05704⁰⁵⁷⁰⁴

Species

D. melanogaster

Name

FlyBase ID

FBal0326358

Feature type

allele

Associated gene

ms(2)05704

Associated Insertion(s)

Carried in Construct

Also Known As

ms(2)46C

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

male fertile (with Df(2R)B5)

(Cenci et al., 2015)

male sterile

(Cenci et al., 2015)

male sterile | recessive

(Spradling et al., 1999, Fabrizio et al., 1998)

viable

(Fabrizio et al., 1998)

Phenotype Manifest In

primary spermatocyte cyst

(Fabrizio et al., 1998)

spermatid

(Cenci et al., 2015, Fabrizio et al., 1998, Castrillon et al., 1993)

spermatozoon

(Fabrizio et al., 1998)

Detailed Description

Statement

Reference

ms(2)05704⁰⁵⁷⁰⁴ homozygous males are sterile and show spermatid defects.

(Cenci et al., 2015)

Mutants show male sterility, with highly elongated, immobile, blebbed sperm tails, disrupted individualisation complexes and scattered spermatid nuclei.

(Fabrizio et al., 1998)

Elongated spermatid nuclei are dispersed.

(Castrillon et al., 1993)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Complements

peo^h

(Cenci et al., 2015)

peo¹

(Cenci et al., 2015)

peo²⁷²³

(Cenci et al., 2015)

peo¹⁵²⁷

(Cenci et al., 2015)

peo^p112

(Cenci et al., 2015)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

11768

cn¹ P{PZ}peo⁰⁵⁷⁰⁴ ms(2)05704⁰⁵⁷⁰⁴/CyO; ry⁵⁰⁶ e¹

Notes on Origin

Discoverer

Separable from: P{PZ}peo⁰⁵⁷⁰⁴.

(Cenci et al., 2015)

The male sterility of the '05704' chromosome (represented in FlyBase by ms(2)05704⁰⁵⁷⁰⁴ does not map to the P{PZ}peo⁰⁵⁷⁰⁴ insertion; males transheterozygous for the P{PZ}peo⁰⁵⁷⁰⁴ insertion and Df(2R)B5 (a deficiency that uncovers peo) are fully fertile.

(Cenci et al., 2015)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (6)

Reported As

Symbol Synonym

cbx⁰⁵⁷⁰⁴

(Cenci et al., 2015)

ms(2)05704

(Spradling et al., 1999)

ms(2)05704⁰⁵⁷⁰⁴

ms(2)46C

(Cenci et al., 2015, Fabrizio et al., 1998, Castrillon et al., 1993)

ms(2)46C⁰⁵⁷⁰⁴

ms(2)ry46C

Name Synonyms

Secondary FlyBase IDs

FBal0028437

References (5)

Report Sections

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