FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Sec71ΔHDS2-4.UAS
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General Information
Symbol
Dmel\Sec71ΔHDS2-4.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0326758
Feature type
allele
Associated gene
Dmel\Sec71
Associated Insertion(s)
Carried in Construct
P{UAS-Sec71.ΔHDS2-4}
Key Links
Transgenic product class
inframe_deletion
(Wang et al., 2017)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Wang et al., 2017)
Mutagen
in vitro construct
(Wang et al., 2017)
Progenitor genotype
Carried in construct
P{UAS-Sec71.ΔHDS2-4}
Cytology
Description

UAS regulatory sequences drive expression of Sec71 which lacks the HDS domains 2-4.

(Wang et al., 2017)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Sec71
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Sec71ΔHDS2-4.UAS/Scer\GAL4ppk.PU rescues Sec71HMS00357

      (Wang et al., 2017)
      Comments

      The co-expression of Sec71ΔHDS2-4.Scer\UAS fully rescues both the dendritic arborization defects at the white pupa stage and the pruning defects at 16h after puparium formation, observed in dorsal multidendritic ddaC neurons upon the expression of Sec71HMS00357 under the combined control of Scer\GAL4ppk.PU and Dicer-2 transgene.

      (Wang et al., 2017)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Sec71ΔHDS2-4.Scer\UAS
      Sec71ΔHDS2-4.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (1)