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General Information
Symbol
Dmel\lbeUAS.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0327176
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-myc-lbe
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of lbe, tagged with Tag:MYC.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expressing lbeUAS.Tag:MYC under the control of Scer\GAL4wg-MD758 results in a significant reduction of axons in the medial-most Fas2-immunopositive fascicle in the embryonic ventral nerve cord.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Co-expressing lbeUAS.Tag:MYC and knUAS.cSa.Tag:HA under the control of either Scer\GAL4elav-C155 or Scer\GAL4wg-MD758 in embryos results in the formation of ectopic ap-expressing neurons which project axons into a common medial fascicle. This in turn leads to the loss of lateral longitudinal fascicles and an overall reduction of the number of longitudinal fascicles. Co-expression under the control of Scer\GAL4wg-MD758 results in a loss of motor neuron projections in thoracic nerves.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
lbeScer\UAS.T:Hsap\MYC
lbeUAS.Tag:MYC
Name Synonyms
Secondary FlyBase IDs
    References (3)