FB2026_02 , released June 18, 2026
Allele: Dmel\cherlong.UAS
Open Close
General Information
Symbol
Dmel\cherlong.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0335701
Feature type
allele
Associated gene
Dmel\cher
Associated Insertion(s)
Carried in Construct
PBac{UAS-cher.long}
Key Links
Transgenic product class
cDNA
(Jeong et al., 2017)
wild_type
(Jeong et al., 2017)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Jeong et al., 2017)
wild_type
(Jeong et al., 2017)
Mutagen
in vitro construct
(Jeong et al., 2017)
Progenitor genotype
Carried in construct
PBac{UAS-cher.long}
Cytology
Description

UASt regulatory sequences drive expression of the open reading frame of the long cher isoform (derived from cDNA clone GH12209).

(Jeong et al., 2017)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
cher
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      cherlong.UAS/Scer\GAL4NP6597 rescues cherNP6597/cherQ1042X

      (Jeong et al., 2017)
      Partially rescues

      cherlong.UAS/Scer\GAL4sca-537.4 partially rescues cherEPSΔ5

      (Jeong et al., 2017)

      cherlong.UAS/Scer\GAL4VGlut1-OK371 partially rescues cherEPSΔ5

      (Jeong et al., 2017)

      cherlong.UAS/Scer\GAL4elav.PLu partially rescues cherEPSΔ5

      (Jeong et al., 2017)
      Comments

      Expression of cherlong.Scer\UAS under the control of any of the following: Scer\GAL4sca-537.4, Scer\GAL4VGlut-OK371 and Scer\GAL4elav.PLu significantly improves the axon guidance defects observed in intersegmental nerve b motor axons of cherEPSΔ5 mutant embryos. Scer\GAL4cher-NP6597-controlled expression (a Gal4 driver inherent to the cherNP6597 allele) also rescues axon pathfinding defects observed in cherQ1042X/cherNP6597 transheterozygous embryos.

      (Jeong et al., 2017)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      cherlong.Scer\UAS
      cherlong.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (1)