FlyBase Allele Report: Dmel\Hcs[HMC06540]

General Information

Symbol

Dmel\Hcs^HMC06540

Species

D. melanogaster

Name

FlyBase ID

FBal0337009

Feature type

allele

Associated gene

Dmel\Hcs

Associated Insertion(s)

Carried in Construct

P{TRiP.HMC06540}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Perkins et al., 2009)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Perkins et al., 2009)

Mutagen

in vitro construct

(Perkins et al., 2009)

Progenitor genotype

Carried in construct

P{TRiP.HMC06540}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Perkins et al., 2009)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMC06540

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased cell number | oogenesis, with Scer\GAL4^{VP16.nanos.UTR}

(Amartuvshin et al., 2025)

decreased size | oogenesis, with Scer\GAL4^{VP16.nanos.UTR}

(Amartuvshin et al., 2025)

female semi-sterile, with Scer\GAL4^{VP16.nanos.UTR}

(Amartuvshin et al., 2025)

male fertile, with Scer\GAL4^{VP16.nanos.UTR}

(Amartuvshin et al., 2025)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Hcs^HMC06540, Scer\GAL4^{VP16.nanos.UTR} has decreased cell number | oogenesis phenotype, suppressible | partially by whd^HMS00040, Scer\GAL4^{VP16.nanos.UTR}

(Amartuvshin et al., 2025)

Hcs^HMC06540, Scer\GAL4^{VP16.nanos.UTR} has female semi-sterile phenotype, suppressible | partially by whd^HMS00040, Scer\GAL4^{VP16.nanos.UTR}

(Amartuvshin et al., 2025)

Hcs^HMC06540, Scer\GAL4^{VP16.nanos.UTR} has decreased size | oogenesis phenotype, suppressible by whd^HMS00040, Scer\GAL4^{VP16.nanos.UTR}

(Amartuvshin et al., 2025)

Phenotype Manifest In

Suppressed by

Statement

Reference

Hcs^HMC06540, Scer\GAL4^{VP16.nanos.UTR} has lipid droplet | decreased number phenotype, suppressible | partially by whd^HMS00040, Scer\GAL4^{VP16.nanos.UTR}

(Amartuvshin et al., 2025)

Hcs^HMC06540, Scer\GAL4^{VP16.nanos.UTR} has female germline cyst phenotype, suppressible by whd^HMS00040, Scer\GAL4^{VP16.nanos.UTR}

(Amartuvshin et al., 2025)

Hcs^HMC06540, Scer\GAL4^{VP16.nanos.UTR} has female germline stem cell | decreased number phenotype, suppressible | partially by whd^HMS00040, Scer\GAL4^{VP16.nanos.UTR}

(Amartuvshin et al., 2025)

Hcs^HMC06540, Scer\GAL4^{VP16.nanos.UTR} has female fusome phenotype, suppressible by whd^HMS00040, Scer\GAL4^{VP16.nanos.UTR}

(Amartuvshin et al., 2025)

Hcs^HMC06540, Scer\GAL4^{VP16.nanos.UTR} has oocyte phenotype, suppressible by whd^HMS00040, Scer\GAL4^{VP16.nanos.UTR}

(Amartuvshin et al., 2025)

Hcs^HMC06540, Scer\GAL4^{VP16.nanos.UTR} has ovary phenotype, suppressible by whd^HMS00040, Scer\GAL4^{VP16.nanos.UTR}

(Amartuvshin et al., 2025)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

77408

y¹ sc^* v¹ sev²¹; P{TRiP.HMC06540}attP40

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Hcs^HMC06540

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections