FlyBase Allele Report: Dmel\kek6[35]

General Information

Symbol

Dmel\kek6³⁵

Species

D. melanogaster

Name

FlyBase ID

FBal0338016

Feature type

allele

Associated gene

Dmel\kek6

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

amorphic allele - molecular evidence

Mutagen

FLPase

Nature of the Allele

Allele class

amorphic allele - molecular evidence

(Ulian-Benitez et al., 2017)

Mutagen

FLPase

(Ulian-Benitez et al., 2017)

Progenitor genotype

PBac{RB}e00907

(Ulian-Benitez et al., 2017)

PBac{WH}f05733

(Ulian-Benitez et al., 2017)

Cytology

Description

Deletion that removes the entire kek6 open reading frame.

(Ulian-Benitez et al., 2017)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

Df(3R)ED6361/kek6³⁵ is a non-enhancer of abnormal neuroanatomy | larval stage phenotype of Toll-6^MI02127/Df(3L)BSC578

(Ulian-Benitez et al., 2017)

Df(3R)ED6361/kek6³⁵ is a non-enhancer of abnormal size | larval stage phenotype of Toll-6^MI02127/Df(3L)BSC578

(Ulian-Benitez et al., 2017)

Suppressor of

Statement

Reference

Df(3R)ED6361/kek6³⁵ is a suppressor of abnormal neuroanatomy | larval stage phenotype of Scer\GAL4^Mhc.PU, spz5^UAS.cUBa

(Ulian-Benitez et al., 2017)

Phenotype Manifest In

NOT Enhancer of

Statement

Reference

Df(3R)ED6361/kek6³⁵ is a non-enhancer of neuromuscular junction | larval stage phenotype of Toll-6^MI02127/Df(3L)BSC578

(Ulian-Benitez et al., 2017)

Df(3R)ED6361/kek6³⁵ is a non-enhancer of type I bouton | larval stage phenotype of Toll-6^MI02127/Df(3L)BSC578

(Ulian-Benitez et al., 2017)

Df(3R)ED6361/kek6³⁵ is a non-enhancer of presynaptic active zone | larval stage phenotype of Toll-6^MI02127/Df(3L)BSC578

(Ulian-Benitez et al., 2017)

Df(3R)ED6361/kek6³⁵ is a non-enhancer of axon | larval stage phenotype of Toll-6^MI02127/Df(3L)BSC578

(Ulian-Benitez et al., 2017)

Suppressor of

Statement

Reference

Df(3R)ED6361/kek6³⁵ is a suppressor of neuromuscular junction | larval stage phenotype of Scer\GAL4^Mhc.PU, spz5^UAS.cUBa

(Ulian-Benitez et al., 2017)

Df(3R)ED6361/kek6³⁵ is a suppressor of terminal bouton | larval stage phenotype of Scer\GAL4^Mhc.PU, spz5^UAS.cUBa

(Ulian-Benitez et al., 2017)

Additional Comments

Genetic Interactions

Statement

Reference

kek6³⁵/Df(3R)ED6361 transheterozygosity suppresses the increased number of larval neuromuscular junction terminal boutons resulting from the expression of spz5^UAS.cUBa under the control of Scer\GAL4^Mhc.PU, and does not enhance the NMJ defects of Toll-6^MI02127/Df(3L)BSC578 transheterozygotes (i.e. decreases in the number of type Ib boutons, in the axonal length, in the number of NMJ branch points and in the number of active zones)

(Ulian-Benitez et al., 2017)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

kek6³⁵

(Ulian-Benitez et al., 2017)

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

Open Close