FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\spz5UAS.cUBa
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General Information
Symbol
Dmel\spz5UAS.cUBa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Ulian-Benitez
FlyBase ID
FBal0338013
Feature type
allele
Associated gene
Dmel\spz5
Associated Insertion(s)
Carried in Construct
P{UAS-spz5.FL}
Also Known As
UAS-DNT2-FL
Key Links
Transgenic product class
wild_type
(Ulian-Benitez et al., 2017)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Ulian-Benitez et al., 2017)
Mutagen
in vitro construct
(Ulian-Benitez et al., 2017)
Progenitor genotype
Carried in construct
P{UAS-spz5.FL}
Cytology
Description

UAS regulatory sequences drive expression of full-length spz5.

(Ulian-Benitez et al., 2017)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
spz5
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The expression of spz5UAS.cUBa under the control of Scer\GAL4Mhc.PU leads to significant increases in the axonal length, in the total number of terminal boutons, in the number of terminal branches and in the number of active zones at the larval NMJ, as compared to controls. Expression under the control of Scer\GAL4Toll-6-D42 also leads to a significant increase in the number of active zones at the larval NMJ, as compared to controls.

      (Ulian-Benitez et al., 2017)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The increased number of larval neuromuscular junction terminal boutons resulting from the expression of spz5UAS.cUBa under the control of Scer\GAL4Mhc.PU is suppressed by kek635/Df(3R)ED6361 transheterozygosity.

      (Ulian-Benitez et al., 2017)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      spz5Scer\UAS.cUBa
      spz5UAS.cUBa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Ulian-Benitez
      Secondary FlyBase IDs
        References (2)