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General Information
Symbol
Dmel\barrE831
Species
D. melanogaster
Name
FlyBase ID
FBal0340394
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Deletion of base pairs 145 and 146 in the first coding exon leads to a frame shift and stop signal 12 codons downstream, resulting in a mutant protein 59 aa long (rather than the wild-type 735 aa).

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

barrE831 homozygous and barrE831/barrL305 transheterozygous embryos show variable muscle pattern defects, which may include: misshaped and disoriented muscles, missing muscles and/or "holes" in the muscle pattern; distorted pharynx musculature; heart cells are occasionally missing or duplicated. These musculature defects are not observed in barrE831/Df(2L)Exel7077 transheterozygotes that also express barrUASp.cOa.EGFP under the control of Scer\GAL4da.PU.

barrE831 homozygous embryos also show a disturbed central nervous system, as compared to controls.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (1)