FlyBase Allele Report: Scer\GAL4[kirre-rP298-G4]

In the adult optic lobe, ScerGAL4^{kirre-rP298-G4} drives expression in in three layers of the distal medulla; this includes the M3 layer, which is innervated by R8 axons. This pattern is also observed at 55 hr APF.

(Bazigou et al., 2007)

Marker for

muscle founder cell

(Johnson et al., 2013)

Reflects expression of

kirre

(Brunetti et al., 2015, Johnson et al., 2013, Susic-Jung et al., 2012, Rotkopf et al., 2011, Bazigou et al., 2007)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal cell shape | embryonic stage, with Tm2^{E54K.UAS.EGFP}

(Williams et al., 2015)

lethal - all die during pharate adult stage, with Scer\GAL4^sns.PK, sing^GD3396

(Brunetti et al., 2015)

viable, with sing^GD3396

(Brunetti et al., 2015)

Phenotype Manifest In

adult muscle system, with Scer\GAL4^sns.PK, sing^GD3396

(Brunetti et al., 2015)

embryonic/larval salivary gland | embryonic stage, with FoxL1^UAS.cHa

(Hanlon and Andrew, 2016)

embryonic myoblast, with Arf6^T27N.UAS

(Chen et al., 2003)

embryonic myoblast, with Tm2^{E54K.UAS.EGFP}

(Williams et al., 2015)

embryonic somatic muscle cell | embryonic stage 16, with Nin^UAS.mEosFP

(Rosen et al., 2019)

larval muscle system | embryonic stage, with barr^E831/Df(2L)Exel7077, barr^{UASp.cOa.EGFP}

(Jacobs, 2018.7.9)

muscle cell of dorsal oblique muscle 2 | embryonic stage, with Tm2^{E54K.UAS.EGFP}

(Williams et al., 2015)

muscle cell of lateral longitudinal muscle 1 | embryonic stage, with Tm2^{E54K.UAS.EGFP}

(Williams et al., 2015)

muscle cell of lateral transverse muscle 1 | embryonic stage, with Tm2^{E54K.UAS.EGFP}

(Williams et al., 2015)

muscle cell of lateral transverse muscle 2 | embryonic stage, with Tm2^{E54K.UAS.EGFP}

(Williams et al., 2015)

muscle cell of lateral transverse muscle 3 | embryonic stage, with Tm2^{E54K.UAS.EGFP}

(Williams et al., 2015)

muscle cell of mesothoracic dorsal acute muscle 3, with Ubx^Ia.UAS

(Enriquez et al., 2010)

muscle cell of metathoracic dorsal acute muscle 3, with Ubx^Ia.UAS

(Enriquez et al., 2010)

myoblast, with Rho1^72O, Rho1^N19.UAS

(Kim et al., 2015)

myoblast, with Rho1^N19.UAS

(Kim et al., 2015)

nucleus | embryonic stage 16, with Nin^UAS.mEosFP

(Rosen et al., 2019)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Tm2^1.UAS.EGFP/Scer\GAL4^{kirre-rP298-G4} is a suppressor | partially of abnormal cell shape | embryonic stage phenotype of hoip¹

(Williams et al., 2015)

Tm2^2.UAS.EGFP/Scer\GAL4^{kirre-rP298-G4} is a suppressor | partially of abnormal cell shape | embryonic stage phenotype of hoip¹

(Williams et al., 2015)

Tm2^3.UAS.EGFP/Scer\GAL4^{kirre-rP298-G4} is a suppressor | partially of abnormal cell shape | embryonic stage phenotype of hoip¹

(Williams et al., 2015)

Scer\GAL4^{kirre-rP298-G4}/Tm2^{cDNA.UAS.EGFP} is a suppressor | partially of abnormal cell shape | embryonic stage phenotype of hoip¹

(Williams et al., 2015)

Phenotype Manifest In

Enhanced by

Statement

Reference

Nin^UAS.mEosFP, Scer\GAL4^{kirre-rP298-G4} has nucleus | embryonic stage 16 phenotype, enhanceable by ens[+]/ens^swo

(Rosen et al., 2019)

Nin^UAS.mEosFP, Scer\GAL4^{kirre-rP298-G4} has embryonic somatic muscle cell | embryonic stage 16 phenotype, enhanceable by ens[+]/ens^swo

(Rosen et al., 2019)

Suppressed by

Statement

Reference

Rho1^72O, Rho1^N19.UAS, Scer\GAL4^{kirre-rP298-G4} has myoblast phenotype, suppressible | partially by Fim^UAS.Venus, Scer\GAL4^{kirre-rP298-G4}

(Kim et al., 2015)

Suppressor of

Statement

Reference

Rho1^UASp.GFP/Scer\GAL4^{kirre-rP298-G4} is a suppressor of myoblast phenotype of Ced-12⁵⁰, Rho1^72O

(Kim et al., 2015)

Fim^UAS.Venus, Scer\GAL4^{kirre-rP298-G4} is a suppressor | partially of myoblast phenotype of Rho1^72O, Rho1^N19.UAS, Scer\GAL4^{kirre-rP298-G4}

(Kim et al., 2015)

Tm2^1.UAS.EGFP/Scer\GAL4^{kirre-rP298-G4} is a suppressor | partially of myotube | embryonic stage phenotype of hoip¹

(Williams et al., 2015)

Tm2^1.UAS.EGFP/Scer\GAL4^{kirre-rP298-G4} is a suppressor | partially of muscle cell of lateral longitudinal muscle 1 | embryonic stage phenotype of hoip¹

(Williams et al., 2015)

Tm2^1.UAS.EGFP/Scer\GAL4^{kirre-rP298-G4} is a suppressor | partially of muscle cell of lateral transverse muscle 1 | embryonic stage phenotype of hoip¹

(Williams et al., 2015)

Tm2^1.UAS.EGFP/Scer\GAL4^{kirre-rP298-G4} is a suppressor | partially of muscle cell of lateral transverse muscle 2 | embryonic stage phenotype of hoip¹

(Williams et al., 2015)

Tm2^1.UAS.EGFP/Scer\GAL4^{kirre-rP298-G4} is a suppressor | partially of muscle cell of lateral transverse muscle 3 | embryonic stage phenotype of hoip¹

(Williams et al., 2015)

Tm2^2.UAS.EGFP/Scer\GAL4^{kirre-rP298-G4} is a suppressor | partially of myotube | embryonic stage phenotype of hoip¹

(Williams et al., 2015)

Tm2^2.UAS.EGFP/Scer\GAL4^{kirre-rP298-G4} is a suppressor | partially of muscle cell of lateral longitudinal muscle 1 | embryonic stage phenotype of hoip¹

(Williams et al., 2015)

Tm2^2.UAS.EGFP/Scer\GAL4^{kirre-rP298-G4} is a suppressor | partially of muscle cell of lateral transverse muscle 1 | embryonic stage phenotype of hoip¹

(Williams et al., 2015)

Tm2^2.UAS.EGFP/Scer\GAL4^{kirre-rP298-G4} is a suppressor | partially of muscle cell of lateral transverse muscle 2 | embryonic stage phenotype of hoip¹

(Williams et al., 2015)

Tm2^2.UAS.EGFP/Scer\GAL4^{kirre-rP298-G4} is a suppressor | partially of muscle cell of lateral transverse muscle 3 | embryonic stage phenotype of hoip¹

(Williams et al., 2015)

Tm2^3.UAS.EGFP/Scer\GAL4^{kirre-rP298-G4} is a suppressor | partially of myotube | embryonic stage phenotype of hoip¹

(Williams et al., 2015)

Tm2^3.UAS.EGFP/Scer\GAL4^{kirre-rP298-G4} is a suppressor | partially of muscle cell of lateral longitudinal muscle 1 | embryonic stage phenotype of hoip¹

(Williams et al., 2015)

Tm2^3.UAS.EGFP/Scer\GAL4^{kirre-rP298-G4} is a suppressor | partially of muscle cell of dorsal oblique muscle 2 | embryonic stage phenotype of hoip¹

(Williams et al., 2015)

Tm2^3.UAS.EGFP/Scer\GAL4^{kirre-rP298-G4} is a suppressor | partially of embryonic myoblast phenotype of hoip¹

(Williams et al., 2015)

Tm2^3.UAS.EGFP/Scer\GAL4^{kirre-rP298-G4} is a suppressor of sarcomere | embryonic stage phenotype of hoip¹

(Williams et al., 2015)

Scer\GAL4^{kirre-rP298-G4}/Tm2^{cDNA.UAS.EGFP} is a suppressor | partially of myotube | embryonic stage phenotype of hoip¹

(Williams et al., 2015)

Scer\GAL4^{kirre-rP298-G4}/Tm2^{cDNA.UAS.EGFP} is a suppressor | partially of muscle cell of lateral longitudinal muscle 1 | embryonic stage phenotype of hoip¹

(Williams et al., 2015)

Scer\GAL4^{kirre-rP298-G4}/Tm2^{cDNA.UAS.EGFP} is a suppressor | partially of muscle cell of lateral transverse muscle 1 | embryonic stage phenotype of hoip¹

(Williams et al., 2015)

Scer\GAL4^{kirre-rP298-G4}/Tm2^{cDNA.UAS.EGFP} is a suppressor | partially of muscle cell of lateral transverse muscle 2 | embryonic stage phenotype of hoip¹

(Williams et al., 2015)

Scer\GAL4^{kirre-rP298-G4}/Tm2^{cDNA.UAS.EGFP} is a suppressor | partially of muscle cell of lateral transverse muscle 3 | embryonic stage phenotype of hoip¹

(Williams et al., 2015)

Scer\GAL4^{kirre-rP298-G4}/Hsap\SNU13^UAS.cJa is a suppressor | partially of embryonic somatic muscle cell phenotype of hoip¹

(Johnson et al., 2013)

NOT Suppressor of

Statement

Reference

Rho1^UASp.GFP/Scer\GAL4^{kirre-rP298-G4} is a non-suppressor of myoblast phenotype of Ced-12⁵⁰, Rho1^72O

(Kim et al., 2015)

Tm2^3.UAS.EGFP/Scer\GAL4^{kirre-rP298-G4} is a non-suppressor of muscle cell of lateral transverse muscle 1 | embryonic stage phenotype of hoip¹

(Williams et al., 2015)

Tm2^3.UAS.EGFP/Scer\GAL4^{kirre-rP298-G4} is a non-suppressor of muscle cell of lateral transverse muscle 2 | embryonic stage phenotype of hoip¹

(Williams et al., 2015)

Tm2^3.UAS.EGFP/Scer\GAL4^{kirre-rP298-G4} is a non-suppressor of muscle cell of lateral transverse muscle 3 | embryonic stage phenotype of hoip¹

(Williams et al., 2015)

Scer\GAL4^{kirre-rP298-G4}/Rac1^V12.UAS is a non-suppressor of embryonic myoblast phenotype of mbc^D11.2

(Haralalka et al., 2011)

Scer\GAL4^{kirre-rP298-G4}/mib1^UAS.cWa is a non-suppressor of larval somatic muscle cell | embryonic stage 16 phenotype of mib2¹

(Nguyen et al., 2007)

Scer\GAL4^{kirre-rP298-G4}/neur^UAS.cPa is a non-suppressor of larval somatic muscle cell | embryonic stage 16 phenotype of mib2¹

(Nguyen et al., 2007)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

mib2^UAS.cDa/Scer\GAL4^{kirre-rP298-G4} rescues mib2¹

(Domsch et al., 2017)

mib2^{ΔHERC2A+ZZ.UAS}/Scer\GAL4^{kirre-rP298-G4} rescues mib2¹

(Domsch et al., 2017)

Scer\GAL4^{kirre-rP298-G4}/mib2^ΔZZ.UAS rescues mib2¹

(Domsch et al., 2017)

mib2^ΔHERC2B.UAS/Scer\GAL4^{kirre-rP298-G4} rescues mib2¹

(Domsch et al., 2017)

hoip^UAS.cJa/Scer\GAL4^{kirre-rP298-G4} rescues hoip¹

(Johnson et al., 2013)

rols^7.UAS/Scer\GAL4^{kirre-rP298-G4} rescues rols^1728-20L

(Haralalka et al., 2011)

Scer\GAL4^{kirre-rP298-G4}/mib2^UAS.cNa rescues mib2¹

(Nguyen et al., 2007)

rols^7.UAS/Scer\GAL4^{kirre-rP298-G4} rescues Df(3L)BK9

(Menon and Chia, 2001)

Partially rescues

mib2^ΔMIB.UAS/Scer\GAL4^{kirre-rP298-G4} partially rescues mib2¹

(Domsch et al., 2017)

Scer\GAL4^{kirre-rP298-G4}/Tm2^{cDNA.UAS.EGFP} partially rescues Df(3R)BSC741/Tm2^Δ8-261

(Williams et al., 2015)

Scer\GAL4^{kirre-rP298-G4}/Iqsec^UAS.Tag:HA partially rescues Iqsec^C1-28

(Dottermusch-Heidel et al., 2012)

Scer\GAL4^{kirre-rP298-G4}/mib2^ΔRF.UAS partially rescues mib2¹

(Nguyen et al., 2007)

Fails to rescue

Scer\GAL4^{kirre-rP298-G4}/mib2^ΔANK.UAS fails to rescue mib2¹

(Domsch et al., 2017)

mib2^ΔN-ANK.UAS/Scer\GAL4^{kirre-rP298-G4} fails to rescue mib2¹

(Domsch et al., 2017)

Scer\GAL4^{kirre-rP298-G4}/mib2^ΔC-ANK.UAS fails to rescue mib2¹

(Domsch et al., 2017)

Pak3^UAS.Tag:V5/Scer\GAL4^{kirre-rP298-G4} fails to rescue Pak3^del

(Duan et al., 2012)

mbc^UAS.Tag:HA/Scer\GAL4^{kirre-rP298-G4} fails to rescue mbc^D11.2

(Haralalka et al., 2011)

blow^UAS.cJa/Scer\GAL4^{kirre-rP298-G4} fails to rescue blow¹

(Jin et al., 2011)

Scer\GAL4^{kirre-rP298-G4}/WASp^UAS.cBa fails to rescue Df(3R)3450/WASp^3D3-035

(Schafer et al., 2007)

mbc^UAS.Tag:HA/Scer\GAL4^{kirre-rP298-G4} fails to rescue mbc^D11.2

(Balagopalan et al., 2006)

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

66682

w^* P{GawB}kirre^rP298-G4

92195

P{GawB}kirre^rP298-G4; e^s mbc^D11.2/TM3, P{HZR+6.8Xb}JG1, Sb¹ Ser¹

Notes on Origin

Discoverer

Comments

Expression pattern confirmed as similar to original enhancer trap (P{PZ}rP298).

(Menon and Chia, 2001)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Scer\GAL4^{kirre-rP298-G4}

Scer\GAL4^kirre-rP298

Name Synonyms

Secondary FlyBase IDs

References (47)

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