FB2026_02 , released June 18, 2026
Allele: Dmel\ClC-bUAS.cWa
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General Information
Symbol
Dmel\ClC-bUAS.cWa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Wong
FlyBase ID
FBal0341722
Feature type
allele
Associated gene
Dmel\ClC-b
Associated Insertion(s)
Carried in Construct
PBac{UAS-ClC-b.W}
Key Links
Transgenic product class
cDNA
(Wong et al., 2017)
wild_type
(Wong et al., 2017)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Wong et al., 2017)
wild_type
(Wong et al., 2017)
Mutagen
in vitro construct
(Wong et al., 2017)
Progenitor genotype
Carried in construct
PBac{UAS-ClC-b.W}
Cytology
Description

UASt regulatory sequences drive expression of ClC-b cDNA (from BDGP EST clone RE63672).

(Wong et al., 2017)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
ClC-b
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Individuals expressing ClC-bUAS.cWa under the control of Scer\GAL4He.PZ display a higher capacity to clear E.coli bacteria upon injection, as compared to equally infected controls.

      (Wong et al., 2017)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Statement
      Reference

      ClC-bUAS.cWa, Scer\GAL4He.PZ has abnormal immune response phenotype, suppressible by Trpml1/Trpml[+]

      (Wong et al., 2017)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      ClC-bUAS.cWa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Wong
      Secondary FlyBase IDs
        References (1)