FlyBase Allele Report: Dmel\Yip1d1[2-20]

General Information

Symbol

Dmel\Yip1d1^2-20

Species

D. melanogaster

Name

FlyBase ID

FBal0342892

Feature type

allele

Associated gene

Dmel\Yip1d1

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

loss of function allele

Mutagen

CRISPR/Cas9

Nature of the Allele

Allele class

loss of function allele

(Wang et al., 2018)

Mutagen

CRISPR/Cas9

(Wang et al., 2018)

Progenitor genotype

Cytology

Description

4bp deletion in the first exon of Yip1d1.

(Wang et al., 2018)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

deletion

2L:13,000,491..13,000,494 [-]

Comment:

4 bases are deleted n the first coding exon of Yip1d1. This results in a frameshift and early translation termination.

(Wang et al., 2018)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy | prepupal stage P1 | somatic clone

(Wang et al., 2018)

abnormal neuroanatomy | pupal stage | somatic clone

(Wang et al., 2018)

Phenotype Manifest In

Detailed Description

Statement

Reference

Yip1d1^2-20 mutant ddaC neuron clones show significantly simplified dendrite arbors with fewer dendritic termini in wandering third instar larvae and show strong pruning defects in pupae (16h APF).

(Wang et al., 2018)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

Yip1d1^2-20 is rescued by Yip1d1^{UAS.C-YFP,Tag:HA}/Scer\GAL4^ppk.PU

(Wang et al., 2018)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Yip1d1^2-20

(Wang et al., 2018)

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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