FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\SKΔ
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General Information
Symbol
Dmel\SKΔ
Species
D. melanogaster
Name
FlyBase ID
FBal0343992
Feature type
allele
Associated gene
Dmel\SK
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Walcott et al., 2018)
Mutagen
FLPase
(Walcott et al., 2018)
Progenitor genotype
PBac{WH}SKf01403
(Walcott et al., 2018)
P{XP}d01963
(Walcott et al., 2018)
Cytology
Description

Deletion of the genomic sequence between the two progenitor insertions (P{XP}d01963 and PBac{WH}SKf01403). This removes most of the SK transcription unit.

(Walcott et al., 2018)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      SKΔ mutant larvae have significantly reduced latency to escape behavior following noxious heat stimulation and increased response rate to noxious mechanical stimuli, but not gentle touch, compared to controls.

      (Walcott et al., 2018)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      SKΔ is rescued by SK+tCH321-90C05

      (Walcott et al., 2018)

      SKΔ is rescued by SKUAS.M/Scer\GAL4ppk.1.9

      (Walcott et al., 2018)
      Not rescued by

      SKΔ is not rescued by SKUAS.V/Scer\GAL4ppk.1.9

      (Walcott et al., 2018)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      SKΔ
      ΔSK
      (Walcott et al., 2018)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)