FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Hsap\ADD1UAS.Tag:HA
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General Information
Symbol
Hsap\ADD1UAS.Tag:HA
Species
H. sapiens
Name
FlyBase ID
FBal0344784
Feature type
allele
Associated gene
Hsap\ADD1
Associated Insertion(s)
Carried in Construct
P{UAS-hADD1.WT.HA}
Key Links
Transgenic product class
wild_type
(Gonçalves et al., 2018)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Gonçalves et al., 2018)
Mutagen
in vitro construct
(Gonçalves et al., 2018)
Progenitor genotype
Carried in construct
P{UAS-hADD1.WT.HA}
Cytology
Description

UASt regulatory sequences drive expression of wild-type Hsap\ADD1 that is tagged at the N-terminal end with Tag:HA.

(Gonçalves et al., 2018)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Hsap\ADD1
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      NOT Suppressor of
      Other
      Phenotype Manifest In
      Suppressor of
      NOT Suppressor of
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      htsnull/Df(2R)BSC26 transheterozygotes rescued to adulthood by the co-expression of Hsap\ADD1UAS.Tag:HA with either Hsap\ADD3UAS.Tag:V5 or Hsap\ADD3E659Q.UAS.Tag:V5 under the control of Scer\GAL4αTub84B.PL show a mostly normal heart function: significant decrease in diastolic diameter but not measurable changes in heart period, cardiac output, fractional shortening, or arrhythmia index). There are no defects in nephrocyte number.

      (Gonçalves et al., 2018)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Hsap\ADD1UAS.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (1)