FlyBase Allele Report: Dmel\st[UAS.Venus]

General Information

Symbol

Dmel\st^UAS.Venus

Species

D. melanogaster

Name

FlyBase ID

FBal0345060

Feature type

allele

Associated gene

Dmel\st

Associated Insertion(s)

Carried in Construct

PBac{UAS-Venus-st}

Key Links

Transgenic product class

wild_type

(Cunningham et al., 2018)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Cunningham et al., 2018)

Mutagen

in vitro construct

(Cunningham et al., 2018)

Progenitor genotype

Carried in construct

PBac{UAS-Venus-st}

Cytology

Description

UAS regulatory sequences drive expression of st that is tagged at the N-terminal end with Venus.

(Cunningham et al., 2018)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Tagged with

Venus

yellow fluorescent protein

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates Parkinson's disease 1

modeled by Hsap\SNCA^UAS.cUa

(Cunningham et al., 2018)

modeled by Hsap\SNCA^A53T.UAS

(Cunningham et al., 2018)

modeled by Hsap\SNCA^A30P.UAS

(Cunningham et al., 2018)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

st^UAS.Venus, Scer\GAL4^ple.PF is a suppressor of decreased cell number | adult stage phenotype of Hsap\SNCA^A53T.UAS, Scer\GAL4^ple.PF

(Cunningham et al., 2018)

st^UAS.Venus, Scer\GAL4^ple.PF is a suppressor of abnormal locomotor behavior | adult stage | progressive phenotype of Hsap\SNCA^A53T.UAS, Scer\GAL4^ple.PF

(Cunningham et al., 2018)

st^UAS.Venus, Scer\GAL4^ple.PF is a suppressor of decreased cell number | adult stage phenotype of Hsap\SNCA^A30P.UAS, Scer\GAL4^ple.PF

(Cunningham et al., 2018)

st^UAS.Venus, Scer\GAL4^ple.PF is a suppressor of abnormal locomotor behavior | adult stage | progressive phenotype of Hsap\SNCA^A30P.UAS, Scer\GAL4^ple.PF

(Cunningham et al., 2018)

st^UAS.Venus, Scer\GAL4^ple.PF is a suppressor of decreased cell number | adult stage phenotype of Hsap\SNCA^UAS.cUa, Scer\GAL4^ple.PF

(Cunningham et al., 2018)

st^UAS.Venus, Scer\GAL4^ple.PF is a suppressor of abnormal locomotor behavior | adult stage | progressive phenotype of Hsap\SNCA^UAS.cUa, Scer\GAL4^ple.PF

(Cunningham et al., 2018)

Phenotype Manifest In

Suppressor of

Statement

Reference

st^UAS.Venus, Scer\GAL4^ple.PF is a suppressor of dopaminergic PPL1 neuron phenotype of Hsap\SNCA^A53T.UAS, Scer\GAL4^ple.PF

(Cunningham et al., 2018)

st^UAS.Venus, Scer\GAL4^ple.PF is a suppressor of dopaminergic PPL1 neuron phenotype of Hsap\SNCA^A30P.UAS, Scer\GAL4^ple.PF

(Cunningham et al., 2018)

st^UAS.Venus, Scer\GAL4^ple.PF is a suppressor of dopaminergic PPL1 neuron phenotype of Hsap\SNCA^UAS.cUa, Scer\GAL4^ple.PF

(Cunningham et al., 2018)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Partially rescues

Scer\GAL4^ple.PF/st^UAS.Venus partially rescues st¹

(Cunningham et al., 2018)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

st^UAS.Venus

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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