Open Close
General Information
Symbol
Dmel\mir-252UAS.cLa
Species
D. melanogaster
Name
UAS construct a of Lim
FlyBase ID
FBal0350210
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of an approximately 200bp genomic region that includes the mir-252 pre-miRNA sequence.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expressing mir-252UAS.cLa under the control of Scer\GAL4Cg.PU leads to a reduced fat body with fewer and smaller cells than controls in third instar larvae, a significantly delayed larval-to-pupal transition and defects in anterior spiracle eversion. Adults have a significantly reduced body weight and wing size likely caused by reductions in cell size, but not cell number, compared to controls. There are no differences in larval hatching rate.

Adults expressing mir-252UAS.cLa under the control of Scer\GAL4ppl.PU have a reduced body weight compared to controls.

Expressing mir-252UAS.cLa under the control of Scer\GAL4GMR.PU induces a rough eye phenotype.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
mir-252UAS.cLa
Name Synonyms
UAS construct a of Lim
Secondary FlyBase IDs
    References (1)