FB2026_02 , released June 18, 2026
Allele: Dmel\daedΔ2
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General Information
Symbol
Dmel\daedΔ2
Species
D. melanogaster
Name
FlyBase ID
FBal0351728
Feature type
allele
Associated gene
Dmel\daed
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Munafò et al., 2019)
Mutagen
CRISPR/Cas9
(Munafò et al., 2019)
Progenitor genotype
daed51323
(Czech, 2020.5.6)
Cytology
Description

Deletion resulting in a premature stop codon, predicted to produce a truncated protein (4aa rather than 272aa) lacking all functional domains.

(Munafò et al., 2019)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      daedΔ2 homozygous females lay fewer eggs than controls or heterozygotes, these eggs have abnormal morphology, no dorsal appendages and do not hatch; daedoof1/daedΔ2 transheterozygous females have altered mitochondrial morphology in the ovary, compared to heterozygous controls.

      (Munafò et al., 2019)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      CG10880Δ2
      (Munafò et al., 2019)
      daedΔ2*
      (Czech, 2020.5.6)
      daedΔ2
      (Munafò et al., 2019)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)