FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\daedoof1
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General Information
Symbol
Dmel\daedoof1
Species
D. melanogaster
Name
FlyBase ID
FBal0351729
Feature type
allele
Associated gene
Dmel\daed
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Munafò et al., 2019)
Mutagen
CRISPR/Cas9
(Munafò et al., 2019)
Progenitor genotype
daed51323
(Czech, 2020.5.6)
Cytology
Description

Deletion causing a frameshift, predicted to produce a truncated protein (146aa rather than 272aa) lacking all functional domains.

(Munafò et al., 2019)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
delins
2L:2,216,154..2,216,200 [-]
Comment:

47bp deletion and 4bp insertion (TCCA) results in a frameshift just after the new downstream start codon 21bp downstream of the annotated one. The strain in which the mutation was made carries a mutation (ATG to AAG) in the wild type start codon.

Inserted_sequence:

TTCA

(Czech, 2020.5.6)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      daedoof1/daedΔ2 mutant females have altered mitochondrial morphology in the ovary, compared to heterozygous controls.

      (Munafò et al., 2019)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      CG10880oof1
      (Munafò et al., 2019)
      daedoof1
      (Czech, 2020.5.6, Munafò et al., 2019)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)