FB2026_02 , released June 18, 2026
Allele: Dmel\Ankle2IGFP
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General Information
Symbol
Dmel\Ankle2IGFP
Species
D. melanogaster
Name
FlyBase ID
FBal0358504
Feature type
allele
Associated gene
Dmel\Ankle2
Associated Insertion(s)
TI{PT-GFSTF.un}Ankle2IGFP
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
phiC31 integrase
(Link et al., 2019)
Progenitor genotype
TI{CRIMIC.GT14}Ankle2CRIMIC
(Link et al., 2019)
Associated Insertion(s)
TI{PT-GFSTF.un}Ankle2IGFP
Cytology
Description

The RMCE cassette in the TI{CRIMIC.GT14}Ankle2CRIMIC insertion has been replaced with a TI{PT-GFSTF.un} cassette.

(Link et al., 2019)
Allele components
Component
Use(s)
Inserted element
TI{PT-GFSTF.un}
Tagged with
EGFP
Tag:CALI(TC)
Tag:CS(TEVp)
Tag:FLAG
Tag:StrepII
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Ankle2IGFP mutant third instar larvae exhibit a severely reduced brain volume, as compared to controls.

      (Link et al., 2019)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      Ankle2IGFP is rescued by Ankle2GFPR

      (Link et al., 2019)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Ankle2IGFP
      (Link et al., 2019)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)