FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\shgΔS+LK
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General Information
Symbol
Dmel\shgΔS+LK
Species
D. melanogaster
Name
FlyBase ID
FBal0358645
Feature type
allele
Associated gene
Dmel\shg
Associated Insertion(s)
TI{TI}shgΔS+LK
Carried in Construct
Key Links
Genomic Maps

Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Chen et al., 2017)
Mutagen
ends-out gene targeting
(Chen et al., 2017)
Progenitor genotype
Associated Insertion(s)
TI{TI}shgΔS+LK
Cytology
Description

22aa within the shg conserved serine cluster is replaced with a generic 22aa linker.

(Chen et al., 2017)

Tagged with GFP at the C-terminus.

(Chen et al., 2017)
Allele components
Component
Use(s)
Tagged with
GFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
MNV
2R:21,050,929..21,050,994 [-]
Comment:

22aa within the shg conserved serine cluster is replaced with a generic 22aa linker.

Inserted_sequence:

NNNNNNNNNNNNNNNNNNNNNN

(Chen et al., 2017)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Third instar larval wing disc clones of shgΔS+LK fail to form discernible adherens junctions.

      (Chen et al., 2017)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      DE-CadΔS+LK
      (Chen et al., 2017)
      shgΔS+LK
      Name Synonyms
      Secondary FlyBase IDs
        References (1)