FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Dso2Δ
Open Close
General Information
Symbol
Dmel\Dso2Δ
Species
D. melanogaster
Name
FlyBase ID
FBal0358828
Feature type
allele
Associated gene
Dmel\Dso2
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Cohen et al., 2020)
Mutagen
CRISPR/Cas9
(Cohen et al., 2020)
Progenitor genotype
Cytology
Description

Deletion of the entire coding sequence for Dso2. (The 5' endpoint lies within 100 bp of the transcriptional start site to minimize potential disruption of elements in the regulatory region between Dso1 and Dso2.

(Cohen et al., 2020)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Survival of Dso2Δ flies is significantly less than controls following systemic infection of F. verticillioides.

      (Cohen et al., 2020)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Statement
      Reference

      Dso2Δ has abnormal immune response | adult stage phenotype, suppressible | partially by Dso1BomS3.PC

      (Cohen et al., 2020)

      Dso2Δ has increased mortality | conditional phenotype, suppressible | partially by Dso1BomS3.PC

      (Cohen et al., 2020)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      Dso2Δ is rescued by Dso2BomS3.PC

      (Cohen et al., 2020)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Dso2Δ
      Δdso2
      (Cohen et al., 2020)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)