FB2026_02 , released June 18, 2026
Allele: Dmel\FhosI966A
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General Information
Symbol
Dmel\FhosI966A
Species
D. melanogaster
Name
FlyBase ID
FBal0361252
Feature type
allele
Associated gene
Dmel\Fhos
Associated Insertion(s)
TI{TI}FhosI966A
Carried in Construct
Key Links
Genomic Maps

Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Shwartz et al., 2016)
Mutagen
CRISPR/Cas9
(Shwartz et al., 2016)
gene targeting by homologous recombination
(Shwartz et al., 2016)
Progenitor genotype
Associated Insertion(s)
TI{TI}FhosI966A
Cytology
Description

Amino acid replacement: I966A.

(Shwartz et al., 2016)

CRISPR/Cas9-induced point mutation in Fhos generates a single amino acid substitution, I966A (according to residue numbering of the short form of Fhos).

(Shwartz et al., 2016)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
MNV
3L:8,790,239..8,790,240 [+]
Nucleotide change:

AT8790239GC

Amino acid change:

I966A | Fhos-PA; I966A | Fhos-PB; I966A | Fhos-PD; I966A | Fhos-PE; I784A | Fhos-PF; I725A | Fhos-PG; I1317A | Fhos-PH; I2101A | Fhos-PI; I2101A | Fhos-PJ

Reported amino acid change:

I966A

Comment:

Single amino acid substitution I966A relative to Fhos-PA. The amino acid change requires substitution at two bases in the codon. Site of nucleotide substitution in mutant inferred by FlyBase curator based on reported amino acid change.

(Shwartz et al., 2016)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
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      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
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      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
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      Xenogenetic Interactions
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      Complementation and Rescue Data
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      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      FhosI966A
      (Shwartz et al., 2016)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)