FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\sggPQ-SFS
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General Information
Symbol
Dmel\sggPQ-SFS
Species
D. melanogaster
Name
FlyBase ID
FBal0362434
Feature type
allele
Associated gene
Dmel\sgg
Associated Insertion(s)
TI{TI}sggPQ-SFS
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
CRISPR/Cas9
(Korona et al., 2020)
gene targeting by homologous recombination
(Korona et al., 2020)
Progenitor genotype
Associated Insertion(s)
TI{TI}sggPQ-SFS
Cytology
Description

A Tag:StrepII-3xTag:FLAG-Tag:StrepII (SFS) multi-tag cassette has been inserted into the endogenous sgg locus, such that it tags an internal exon of the PQprotein isoform (this also tags isoforms PM, PP and PR).

(Korona et al., 2020)
Allele components
Component
Use(s)
Tagged with
Tag:FLAG
Tag:StrepII
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter or direct label
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      embryonic stage 16
      embryonic/larval salivary gland
      (Korona et al., 2020)
      embryonic/larval proventriculus
      (Korona et al., 2020)
      Additional Information
      Statement
      Reference

      At later stages expression is strong in the salivary glands and proventriculus.

      (Korona et al., 2020)
       
      Marker for
      Reflects expression of
      sgg
      (Korona et al., 2020)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      sggPQ-SFS
      Name Synonyms
      Secondary FlyBase IDs
        References (1)