FlyBase Allele Report: Dmel\Sp1[ΔBTD-box]

General Information

Symbol

Dmel\Sp1^ΔBTD-box

Species

D. melanogaster

Name

FlyBase ID

FBal0363186

Feature type

allele

Associated gene

Dmel\Sp1

Associated Insertion(s)

TI{TI}Sp1^ΔBTD-box

Carried in Construct

Key Links

Allele class

loss of function allele

Mutagen

Nature of the Allele

Allele class

loss of function allele

(Blom-Dahl et al., 2020)

Mutagen

phiC31 integrase

(Blom-Dahl et al., 2020)

cre recombinase

(Blom-Dahl et al., 2020)

Progenitor genotype

TI{TI}Sp1^HR

(Blom-Dahl et al., 2020)

Associated Insertion(s)

TI{TI}Sp1^ΔBTD-box

Cytology

Description

A mutant third exon of Sp1 lacking the BTD-box is inserted into the attP site in TI{TI}Sp1^HR. The reporter gene and selectable marker have been removed via P1\cre.

(Blom-Dahl et al., 2020)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased size | adult stage

(Blom-Dahl et al., 2020)

decreased size | adult stage (with Df(1)btd-Sp1)

(Blom-Dahl et al., 2020)

visible | adult stage

(Blom-Dahl et al., 2020)

visible | adult stage (with Df(1)btd-Sp1)

(Blom-Dahl et al., 2020)

Phenotype Manifest In

leg | adult stage

(Blom-Dahl et al., 2020)

leg | adult stage (with Df(1)btd-Sp1)

(Blom-Dahl et al., 2020)

segment of leg | adult stage

(Blom-Dahl et al., 2020)

segment of leg | adult stage (with Df(1)btd-Sp1)

(Blom-Dahl et al., 2020)

sex comb | adult stage

(Blom-Dahl et al., 2020)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

Sp1^ΔBTD-box has decreased size | adult stage phenotype, non-enhanceable by btd^ΔBTD-box.4

(Blom-Dahl et al., 2020)

Sp1^ΔBTD-box has visible | adult stage phenotype, non-enhanceable by btd^ΔBTD-box.4

(Blom-Dahl et al., 2020)

NOT suppressed by

Statement

Reference

Sp1^ΔBTD-box has decreased size | adult stage phenotype, non-suppressible by btd^ΔBTD-box.4

(Blom-Dahl et al., 2020)

Sp1^ΔBTD-box has visible | adult stage phenotype, non-suppressible by btd^ΔBTD-box.4

(Blom-Dahl et al., 2020)

Enhancer of

Statement

Reference

Sp1^ΔBTD-box is an enhancer of decreased size | adult stage phenotype of Df(1)btd-Sp1/btd^ΔBTD-box.4

(Blom-Dahl et al., 2020)

Sp1^ΔBTD-box is an enhancer of visible | adult stage phenotype of Df(1)btd-Sp1/btd^ΔBTD-box.4

(Blom-Dahl et al., 2020)

Other

Statement

Reference

Sp1^ΔBTD-box, btd^ΔBTD-box.4 has partially lethal phenotype

(Blom-Dahl et al., 2020)

Sp1^ΔBTD-box/Df(1)btd-Sp1, btd^ΔBTD-box.4 has lethal - all die before end of P-stage phenotype

(Blom-Dahl et al., 2020)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

Sp1^ΔBTD-box has leg | adult stage phenotype, non-enhanceable by btd^ΔBTD-box.4

(Blom-Dahl et al., 2020)

Sp1^ΔBTD-box has segment of leg | adult stage phenotype, non-enhanceable by btd^ΔBTD-box.4

(Blom-Dahl et al., 2020)

NOT suppressed by

Statement

Reference

Sp1^ΔBTD-box has leg | adult stage phenotype, non-suppressible by btd^ΔBTD-box.4

(Blom-Dahl et al., 2020)

Sp1^ΔBTD-box has segment of leg | adult stage phenotype, non-suppressible by btd^ΔBTD-box.4

(Blom-Dahl et al., 2020)

Enhancer of

Statement

Reference

Sp1^ΔBTD-box is an enhancer of leg | adult stage phenotype of Df(1)btd-Sp1/btd^ΔBTD-box.4

(Blom-Dahl et al., 2020)

Sp1^ΔBTD-box is an enhancer of segment of leg | adult stage phenotype of Df(1)btd-Sp1/btd^ΔBTD-box.4

(Blom-Dahl et al., 2020)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Sp1^ΔBTD-box

(Blom-Dahl et al., 2020)

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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