FlyBase Allele Report: Dmel\yki[S168A.UAS.Tag:FLAG]

FB2026_01 , released March 12, 2026

FB2026_01 , released March 12, 2026

Allele: Dmel\yki^{S168A.UAS.Tag:FLAG}

General Information

Symbol

Dmel\yki^{S168A.UAS.Tag:FLAG}

Species

D. melanogaster

Name

FlyBase ID

FBal0363192

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

PBac{UAS-yki.S168A.FLAG}

Key Links

Transgenic product class

missense_variant

(Tyra et al., 2020)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

missense_variant

(Tyra et al., 2020)

Mutagen

in vitro construct

(Tyra et al., 2020)

Progenitor genotype

Carried in construct

PBac{UAS-yki.S168A.FLAG}

Cytology

Description

UAS regulatory sequences drive expression of mutant yki with the S168A mutation, tagged with Tag:FLAG.

(Tyra et al., 2020)

Allele components

Component

Use(s)

Regulatory region(s)

binary expression system - regulatory region

Encoded product / tool

Tagged with

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

increased size | adult stage, with Scer\GAL4^GMR.PF

(Tyra et al., 2020)

visible | adult stage, with Scer\GAL4^GMR.PF

(Tyra et al., 2020)

Phenotype Manifest In

eye, with Scer\GAL4^GMR.PF

(Tyra et al., 2020)

Detailed Description

Statement

Reference

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Scer\GAL4^GMR.PF, yki^{S168A.UAS.Tag:FLAG} has visible | adult stage phenotype, suppressible by Acn^UAS.cNa, Scer\GAL4^GMR.PF

(Tyra et al., 2020)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.Tag:FLAG} has increased size | adult stage phenotype, suppressible by Acn^UAS.cNa, Scer\GAL4^GMR.PF

(Tyra et al., 2020)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.Tag:FLAG} has visible | adult stage phenotype, suppressible by Atg1^UAS.cSa, Scer\GAL4^GMR.PF

(Tyra et al., 2020)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.Tag:FLAG} has increased size | adult stage phenotype, suppressible by Atg1^UAS.cSa, Scer\GAL4^GMR.PF

(Tyra et al., 2020)

Phenotype Manifest In

Suppressed by

Statement

Reference

Scer\GAL4^GMR.PF, yki^{S168A.UAS.Tag:FLAG} has eye phenotype, suppressible by Acn^UAS.cNa, Scer\GAL4^GMR.PF

(Tyra et al., 2020)

Scer\GAL4^GMR.PF, yki^{S168A.UAS.Tag:FLAG} has eye phenotype, suppressible by Atg1^UAS.cSa, Scer\GAL4^GMR.PF

(Tyra et al., 2020)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

yki^{S168A.UAS.Tag:FLAG}

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections