FlyBase Allele Report: Dmel\Tspo[UAS.cRa]

General Information

Symbol

Dmel\Tspo^UAS.cRa

Species

D. melanogaster

Name

UAS construct a of Russi

FlyBase ID

FBal0364444

Feature type

allele

Associated gene

Dmel\Tspo

Associated Insertion(s)

Carried in Construct

PBac{UAS-Tspo.R}

Also Known As

UAS-Tspo

Key Links

Transgenic product class

genomic_DNA

(Russi et al., 2020)

wild_type

(Russi et al., 2020)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

genomic_DNA

(Russi et al., 2020)

wild_type

(Russi et al., 2020)

Mutagen

in vitro construct

(Russi et al., 2020)

Progenitor genotype

Carried in construct

PBac{UAS-Tspo.R}

Cytology

Description

UAS regulatory sequences drive expression of genomic fragment that encodes Tspo.

(Russi et al., 2020)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Tspo

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates Friedreich ataxia 1

modeled by fh^GAAs

(Jullian et al., 2024)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

long lived | RU486 conditional, with Scer\GAL4^{repo.Switch.2301}

(Jullian et al., 2024)

short lived | RU486 conditional, with Scer\GAL4^{elav.Switch.PO}

(Jullian et al., 2024)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Tspo^UAS.cRa/Scer\GAL4^da.Switch.PT is a suppressor | partially of short lived phenotype of fh^GAAs

(Jullian et al., 2024)

Tspo^UAS.cRa/Scer\GAL4^GS.nSyb.PB is a suppressor | partially of short lived phenotype of fh^GAAs

(Jullian et al., 2024)

Scer\GAL4^{repo.Switch.2301}/Tspo^UAS.cRa is a suppressor | partially of short lived phenotype of fh^GAAs

(Jullian et al., 2024)

Scer\GAL4^{repo.Switch.2301}/Tspo^UAS.cRa is a suppressor | partially of decreased rate of movement | adult stage | progressive phenotype of fh^GAAs

(Jullian et al., 2024)

NOT Suppressor of

Statement

Reference

Tspo^UAS.cRa/Scer\GAL4^da.Switch.PT is a non-suppressor of lethal | recessive phenotype of fh^200GAA

(Russi et al., 2020)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Tspo^UAS.cRa

Name Synonyms

UAS construct a of Russi

Secondary FlyBase IDs

References (2)

Report Sections

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