FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Hsap\CHMP4Bshrb.BAC
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General Information
Symbol
Hsap\CHMP4Bshrb.BAC
Species
H. sapiens
Name
FlyBase ID
FBal0366162
Feature type
allele
Associated gene
Hsap\CHMP4B
Associated Insertion(s)
Carried in Construct
M{shrb-hCHMP4B.BAC}
Also Known As
BACshrub-CHMP4B
Key Links
Transgenic product class
cDNA
(Baeumers et al., 2020)
wild_type
(Baeumers et al., 2020)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Baeumers et al., 2020)
wild_type
(Baeumers et al., 2020)
Mutagen
in vitro construct
(Baeumers et al., 2020)
Progenitor genotype
Carried in construct
M{shrb-hCHMP4B.BAC}
Cytology
Description

BAC clone (CH322-47O20) that encompasses shrb, in which the genomic sequence encoding the shrb transcription unit has been replaced by a Hsap\CHMP4B cDNA.

(Baeumers et al., 2020)
Allele components
Component
Use(s)
Regulatory region(s)
shrb
Encoded product / tool
Hsap\CHMP4B
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      NOT Suppressor of
      Other
      Statement
      Reference

      Hsap\CHMP4Bshrb.BAC, shrb4 has sterile phenotype

      (Baeumers et al., 2022)

      Hsap\CHMP4Bshrb.BAC/Hsap\CHMP4Bmut2.shrb.BAC, shrb4 has lethal - all die before end of pupal stage phenotype

      (Baeumers et al., 2022)

      Hsap\CHMP4Bshrb.BAC, shrb4, shrbcDNA.LAP.EGFP has lethal - all die before end of P-stage phenotype

      (Baeumers et al., 2022)

      Hsap\CC2D1BUAS.Tag:HA, Hsap\CHMP4Bshrb.BAC, Hsap\CHMP4Cshrb.BAC, l(2)gd1d7, shrb4 has lethal - all die before end of P-stage phenotype

      (Baeumers et al., 2022)

      Hsap\CHMP4Ashrb.BAC, Hsap\CHMP4Bshrb.BAC, shrb4 has lethal - all die before end of P-stage phenotype

      (Baeumers et al., 2022)

      Hsap\CC2D1BUAS.Tag:HA, Hsap\CHMP4Ashrb.BAC, Hsap\CHMP4Bshrb.BAC, Scer\GAL4unspecified, l(2)gd1d7, shrb4 has lethal - all die before end of pupal stage phenotype

      (Baeumers et al., 2022)

      Hsap\CHMP4Bshrb.BAC, l(2)gd1d7, shrb4 has lethal - all die before end of second instar larval stage phenotype

      (Baeumers et al., 2022)

      Hsap\CC2D1BUAS.Tag:HA, Hsap\CHMP4Bshrb.BAC, Scer\GAL4unspecified, l(2)gd1d7, shrb4 has sterile phenotype

      (Baeumers et al., 2022)

      Hsap\CC2D1AUAS.Tag:HA, Hsap\CHMP4Bshrb.BAC, Scer\GAL4unspecified, l(2)gd1d7, shrb4 has lethal - all die before end of P-stage phenotype

      (Baeumers et al., 2022)

      Hsap\CHMP4Bshrb.BAC, Scer\GAL4unspecified, l(2)gd1UAS.cJa.Tag:HA, l(2)gd1d7, shrb4 has sterile phenotype

      (Baeumers et al., 2022)

      Hsap\CC2D1BΔDM14-1+2R412E.l(2)gd1.Tag:HA, Hsap\CHMP4Bshrb.BAC, l(2)gd1d7, shrb4 has lethal - all die before end of second instar larval stage phenotype

      (Baeumers et al., 2022)

      Hsap\CC2D1BΔDM14-1+2R416E.l(2)gd1.Tag:HA, Hsap\CHMP4Bshrb.BAC, l(2)gd1d7, shrb4 has lethal - all die before end of second instar larval stage phenotype

      (Baeumers et al., 2022)

      Hsap\CC2D1BΔDM14-1-3.l(2)gd1.Tag:HA, Hsap\CHMP4Bshrb.BAC, l(2)gd1d7, shrb4 has lethal - all die before end of second instar larval stage phenotype

      (Baeumers et al., 2022)

      Hsap\CHMP4Bshrb.BAC, Hsap\CHMP4Cshrb.BAC, shrb4 has lethal - all die before end of P-stage phenotype

      (Baeumers et al., 2022)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Hsap\CHMP4Bshrb.BAC
      Name Synonyms
      Secondary FlyBase IDs
        References (2)