FB2026_02 , released June 18, 2026
Allele: Dmel\LP3
Open Close
General Information
Symbol
Dmel\LP3
Species
D. melanogaster
Name
FlyBase ID
FBal0368843
Feature type
allele
Associated gene
Dmel\L
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
CRISPR/Cas9
(Son and Choi, 2020)
Progenitor genotype
Cytology
Description

11bp deletion in the last exon of L. This results in a frameshift in the L-PB product after codon 269, removing most of the zinc-finger motifs.

(Son and Choi, 2020)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
2R:14,462,326..14,462,336 [+]
Comment:

An 11 bp-deletion (GTGGCAATCCG - position 809-819 bp of the L-RB CDS). The mutation leads to a frameshift and an early translation termination after the addition of 5 novel amino acids after A269 of L-PB.

(Choi, 2021.8.18)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      LD0B

      (Son and Choi, 2020)

      Lrev6-3

      (Son and Choi, 2020)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      LP3
      (Son and Choi, 2020)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)