FB2026_02 , released June 18, 2026
Allele: Dmel\Lb6
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General Information
Symbol
Dmel\Lb6
Species
D. melanogaster
Name
FlyBase ID
FBal0368847
Feature type
allele
Associated gene
Dmel\L
Associated Insertion(s)
roo{}L-2
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
CRISPR/Cas9
(Son and Choi, 2020)
Progenitor genotype
L2
(Son and Choi, 2020)
Associated Insertion(s)
roo{}L-2
Cytology
Description

Mutation resulting in a frame-shift from the 14th codon of L-PB followed by a premature stop codon.

(Son and Choi, 2020)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
delins
2R:14,458,806..14,458,811 [+]
Inserted_sequence:

ATGATCC

Comment:

Sequences in L deleted and replaced with ATGATCC, causing a frameshift.

(Son and Choi, 2020)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Selected as a revertant of the L2/+ eye phenotype; 40-80% of heterozygotes show a weak mutant eye phenotype, such as a small dent in the anterior part of the eye.

      (Son and Choi, 2020)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      LD0B

      (Son and Choi, 2020)

      Lrev6-3

      (Son and Choi, 2020)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Lb6
      (Son and Choi, 2020)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)