FlyBase Allele Report: Dmel\Syb[QFVW.UAS]

General Information

Symbol

Dmel\Syb^QFVW.UAS

Species

D. melanogaster

Name

FlyBase ID

FBal0368859

Feature type

allele

Associated gene

Dmel\Syb

Associated Insertion(s)

Carried in Construct

PBac{UAS-Syb.QFVW}

Key Links

Transgenic product class

missense_variant

(Böhme et al., 2021)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

missense_variant

(Böhme et al., 2021)

Mutagen

in vitro construct

(Böhme et al., 2021)

Progenitor genotype

Carried in construct

PBac{UAS-Syb.QFVW}

Cytology

Description

UAS regulatory sequences drive expression of Syb isoform A cDNA (DGRC clone SD05285) in which the Q69/F70 site was exchanged with V/W (to render it insensitive to Ctet\tetX).

(Böhme et al., 2021)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Syb

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Syb^QFVW.UAS is a suppressor of abnormal locomotor behavior | larval stage phenotype of Ctet\tetX^TNT-LC.UAS, Scer\GAL4^Gli.PU

(Böhme et al., 2021)

Syb^QFVW.UAS is a suppressor of increased size | larval stage phenotype of Ctet\tetX^TNT-LC.UAS, Scer\GAL4^Gli.PU

(Böhme et al., 2021)

Syb^QFVW.UAS is a suppressor of abnormal neuroanatomy | larval stage phenotype of Ctet\tetX^TNT-LC.UAS, Scer\GAL4^Gli.PU

(Böhme et al., 2021)

Syb^QFVW.UAS is a suppressor of abnormal locomotor behavior | larval stage phenotype of Ctet\tetX^TNT-LC.UAS, Scer\GAL4^repo

(Böhme et al., 2021)

Syb^QFVW.UAS is a suppressor of increased size | larval stage phenotype of Ctet\tetX^TNT-LC.UAS, Scer\GAL4^repo

(Böhme et al., 2021)

Syb^QFVW.UAS is a suppressor of abnormal neuroanatomy | larval stage phenotype of Ctet\tetX^TNT-LC.UAS, Scer\GAL4^repo

(Böhme et al., 2021)

Phenotype Manifest In

Suppressor of

Statement

Reference

Syb^QFVW.UAS is a suppressor of nerve | larval stage phenotype of Ctet\tetX^TNT-LC.UAS, Scer\GAL4^Gli.PU

(Böhme et al., 2021)

Syb^QFVW.UAS is a suppressor of nerve | larval stage phenotype of Ctet\tetX^TNT-LC.UAS, Scer\GAL4^repo

(Böhme et al., 2021)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Syb^QFVW.UAS

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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