FlyBase Allele Report: Hsap\RELA[p65(AD)::pMag.Ubi]

General Information

Symbol

Hsap\RELA^{p65(AD)::pMag.Ubi}

Species

H. sapiens

Name

FlyBase ID

FBal0374076

Feature type

allele

Associated gene

Hsap\RELA

Associated Insertion(s)

Carried in Construct

P{Ubi-p65(AD)::pMag}

Also Known As

ubi-2xpMag:AD

Key Links

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(di Pietro et al., 2021)

Progenitor genotype

Carried in construct

P{Ubi-p65(AD)::pMag}

Cytology

Description

The Ubi-p63E promoter drives expression of the p65(AD)::pMag hemidriver.

(di Pietro et al., 2021)

Allele components

Component

Use(s)

Encoded product / tool

p65(AD)::pMag

split driver - transcription activation fragment

light-regulated split driver fragment

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased size | adult stage, with RpS12^KK115942, Scer\GAL4^{rn-G4DBD::nMagHigh1}

(El Marzkioui et al., 2025)

decreased size | larval stage, with Akt^HMS00007, Scer\GAL4^{rn-G4DBD::nMagHigh1}

(El Marzkioui et al., 2025)

decreased size | larval stage, with Cyp18a1^UAS.cRa, Scer\GAL4^{rn-G4DBD::nMagHigh1}

(El Marzkioui et al., 2025)

decreased size | larval stage, with EcR^{B1-ΔC655.F645A.UAS}, Scer\GAL4^{rn-G4DBD::nMagHigh1}

(El Marzkioui et al., 2025)

decreased size | larval stage, with Notum^UAS.cGa, Scer\GAL4^{rn-G4DBD::nMagHigh1}

(El Marzkioui et al., 2025)

decreased size | larval stage, with Pten^UAS.cHa, Scer\GAL4^{rn-G4DBD::nMagHigh1}

(El Marzkioui et al., 2025)

decreased size | larval stage, with Scer\GAL4^{rn-G4DBD::nMagHigh1}, brk^UAS.Tag:HA

(El Marzkioui et al., 2025)

decreased size | P-stage, with Akt^HMS00007, Scer\GAL4^{rn-G4DBD::nMagHigh1}

(El Marzkioui et al., 2025)

decreased size | P-stage, with Pten^UAS.cHa, Scer\GAL4^{rn-G4DBD::nMagHigh1}

(El Marzkioui et al., 2025)

decreased size | P-stage, with RpS12^KK115942, Scer\GAL4^{rn-G4DBD::nMagHigh1}

(El Marzkioui et al., 2025)

increased size | larval stage, with InR^A1325D.UAS, Scer\GAL4^{rn-G4DBD::nMagHigh1}

(El Marzkioui et al., 2025)

increased size | larval stage, with Oatp74D^UAS.cOa, Scer\GAL4^{rn-G4DBD::nMagHigh1}

(El Marzkioui et al., 2025)

increased size | larval stage, with Rheb^AV4, Scer\GAL4^{rn-G4DBD::nMagHigh1}

(El Marzkioui et al., 2025)

increased size | larval stage, with Scer\GAL4^{rn-G4DBD::nMagHigh1}, Tsc1^KK102605

(El Marzkioui et al., 2025)

increased size | P-stage, with InR^A1325D.UAS, Scer\GAL4^{rn-G4DBD::nMagHigh1}

(El Marzkioui et al., 2025)

increased size | P-stage, with Oatp74D^UAS.cOa, Scer\GAL4^{rn-G4DBD::nMagHigh1}

(El Marzkioui et al., 2025)

visible | adult stage, with RpS12^KK115942, Scer\GAL4^{rn-G4DBD::nMagHigh1}

(El Marzkioui et al., 2025)

Phenotype Manifest In

wing, with RpS12^KK115942, Scer\GAL4^{rn-G4DBD::nMagHigh1}

(El Marzkioui et al., 2025)

wing | P-stage, with Akt^HMS00007, Scer\GAL4^{rn-G4DBD::nMagHigh1}

(El Marzkioui et al., 2025)

wing | P-stage, with InR^A1325D.UAS, Scer\GAL4^{rn-G4DBD::nMagHigh1}

(El Marzkioui et al., 2025)

wing | P-stage, with Oatp74D^UAS.cOa, Scer\GAL4^{rn-G4DBD::nMagHigh1}

(El Marzkioui et al., 2025)

wing | P-stage, with Pten^UAS.cHa, Scer\GAL4^{rn-G4DBD::nMagHigh1}

(El Marzkioui et al., 2025)

wing | P-stage, with RpS12^KK115942, Scer\GAL4^{rn-G4DBD::nMagHigh1}

(El Marzkioui et al., 2025)

wing disc | larval stage, with Akt^HMS00007, Scer\GAL4^{rn-G4DBD::nMagHigh1}

(El Marzkioui et al., 2025)

wing disc | larval stage, with Cyp18a1^UAS.cRa, Scer\GAL4^{rn-G4DBD::nMagHigh1}

(El Marzkioui et al., 2025)

wing disc | larval stage, with EcR^{B1-ΔC655.F645A.UAS}, Scer\GAL4^{rn-G4DBD::nMagHigh1}

(El Marzkioui et al., 2025)

wing disc | larval stage, with InR^A1325D.UAS, Scer\GAL4^{rn-G4DBD::nMagHigh1}

(El Marzkioui et al., 2025)

wing disc | larval stage, with Notum^UAS.cGa, Scer\GAL4^{rn-G4DBD::nMagHigh1}

(El Marzkioui et al., 2025)

wing disc | larval stage, with Oatp74D^UAS.cOa, Scer\GAL4^{rn-G4DBD::nMagHigh1}

(El Marzkioui et al., 2025)

wing disc | larval stage, with Pten^UAS.cHa, Scer\GAL4^{rn-G4DBD::nMagHigh1}

(El Marzkioui et al., 2025)

wing disc | larval stage, with Rheb^AV4, Scer\GAL4^{rn-G4DBD::nMagHigh1}

(El Marzkioui et al., 2025)

wing disc | larval stage, with Scer\GAL4^{rn-G4DBD::nMagHigh1}, brk^UAS.Tag:HA

(El Marzkioui et al., 2025)

wing disc | larval stage, with Scer\GAL4^{rn-G4DBD::nMagHigh1}, Tsc1^KK102605

(El Marzkioui et al., 2025)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

Hsap\RELA^{p65(AD)::pMag.Ubi}, Scer\GAL4^{rn-G4DBD::nMagHigh1}, Tsc1^UAS.cTa, gig^UAS.cTa has decreased size | larval stage phenotype

(El Marzkioui et al., 2025)

Hsap\RELA^{p65(AD)::pMag.Ubi}, Scer\GAL4^{rn-G4DBD::nMagHigh1}, Tsc1^UAS.cTa, gig^UAS.cTa has decreased size | P-stage phenotype

(El Marzkioui et al., 2025)

Phenotype Manifest In

Other

Statement

Reference

Hsap\RELA^{p65(AD)::pMag.Ubi}, Scer\GAL4^{rn-G4DBD::nMagHigh1}, Tsc1^UAS.cTa, gig^UAS.cTa has wing disc | larval stage phenotype

(El Marzkioui et al., 2025)

Hsap\RELA^{p65(AD)::pMag.Ubi}, Scer\GAL4^{rn-G4DBD::nMagHigh1}, Tsc1^UAS.cTa, gig^UAS.cTa has wing | P-stage phenotype

(El Marzkioui et al., 2025)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Hsap\RELA^{p65(AD)::pMag.Ubi}

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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