FlyBase Allele Report: Hsap\HSPA9[UAS.cZa]

General Information

Symbol

Hsap\HSPA9^UAS.cZa

Species

H. sapiens

Name

UAS construct a of Zhu

FlyBase ID

FBal0374150

Feature type

allele

Associated gene

Hsap\HSPA9

Associated Insertion(s)

Carried in Construct

P{UAS-hHSPA9.Z}

Key Links

Transgenic product class

cDNA

(Zhu et al., 2021)

wild_type

(Zhu et al., 2021)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(Zhu et al., 2021)

wild_type

(Zhu et al., 2021)

Mutagen

in vitro construct

(Zhu et al., 2021)

Progenitor genotype

Carried in construct

P{UAS-hHSPA9.Z}

Cytology

Description

UASt regulatory sequences drive expression of a wild-type Hsap\HSPA9 cDNA.

(Zhu et al., 2021)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Hsap\HSPA9

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates Parkinson's disease

modeled by Hsc70-5^KK100233

(Zhu et al., 2021)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Hsap\HSPA9^UAS.cZa, Scer\GAL4^elav.PU is a suppressor of lethal - all die before end of pupal stage phenotype of Hsc70-5^KK100233, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsap\HSPA9^UAS.cZa, Scer\GAL4^elav.PU is a suppressor | partially of abnormal locomotor behavior | third instar larval stage phenotype of Hsc70-5^KK100233, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsap\HSPA9^UAS.cZa, Scer\GAL4^elav.PU is a suppressor | partially of abnormal locomotor behavior | adult stage phenotype of Hsc70-5^KK100233, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsap\HSPA9^UAS.cZa, Scer\GAL4^elav.PU is a suppressor | partially of visible | adult stage phenotype of Hsc70-5^KK100233, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsap\HSPA9^UAS.cZa, Scer\GAL4^elav.PU is a suppressor of abnormal heat stress response | adult stage phenotype of Hsc70-5^KK100233, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsap\HSPA9^UAS.cZa, Scer\GAL4^elav.PU is a suppressor of paralytic | adult stage | heat sensitive phenotype of Hsc70-5^KK100233, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Phenotype Manifest In

Suppressor of

Statement

Reference

Hsap\HSPA9^UAS.cZa, Scer\GAL4^elav.PU is a suppressor | partially of mitochondrion | third instar larval stage phenotype of Hsc70-5^KK100233, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsap\HSPA9^UAS.cZa, Scer\GAL4^elav.PU is a suppressor | partially of embryonic/larval neuromuscular junction | third instar larval stage phenotype of Hsc70-5^KK100233, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Hsap\HSPA9^UAS.cZa, Scer\GAL4^elav.PU is a suppressor | partially of wing phenotype of Hsc70-5^KK100233, Scer\GAL4^elav.PU

(Zhu et al., 2021)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Hsap\HSPA9^UAS.cZa

Name Synonyms

UAS construct a of Zhu

Secondary FlyBase IDs

References (1)

Report Sections

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