FlyBase Allele Report: Dmel\ppan[Ebox]

General Information

Symbol

Dmel\ppan^Ebox

Species

D. melanogaster

Name

FlyBase ID

FBal0374310

Feature type

allele

Associated gene

Dmel\ppan

Associated Insertion(s)

TI{TI}ppan^Ebox

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

CRISPR/Cas9

Nature of the Allele

Allele class

Mutagen

CRISPR/Cas9

(Zielke et al., 2022)

Progenitor genotype

Associated Insertion(s)

TI{TI}ppan^Ebox

Cytology

Description

The E-box (Myc-binding site) in the promoter region has been replaced with the lexAop sequence (CTGTATATATATACAG).

(Zielke et al., 2022)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

delins

3R:21,116,263..21,116,276 [+]

Inserted_sequence:

CTGTATATATATACAG

Comment:

The indicated region (E-box) is replaced with the lexAop sequence (CTGTATATATATACAG).

(Zielke et al., 2022)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal developmental rate

(Zielke et al., 2022)

decreased size | adult stage

(Zielke et al., 2022)

Phenotype Manifest In

scutellar bristle

(Zielke et al., 2022)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Myc^UAS.cZa, Scer\GAL4^Tub.PU, ppan^Ebox has increased cell death | somatic clone | larval stage phenotype, suppressible | partially by BacA\p35^UAS.cHa, Scer\GAL4^Tub.PU

(Zielke et al., 2022)

Other

Statement

Reference

Myc^UAS.cZa, Scer\GAL4^Tub.PU, ppan^Ebox has increased cell death | somatic clone | larval stage phenotype

(Zielke et al., 2022)

Ecol\lexA^GAD.UAS.cZa, Scer\GAL4^en.PU, ppan^Ebox has increased cell death | somatic clone | larval stage phenotype

(Zielke et al., 2022)

Phenotype Manifest In

Suppressed by

Statement

Reference

Myc^UAS.cZa, Scer\GAL4^Tub.PU, ppan^Ebox has wing disc | somatic clone | larval stage phenotype, suppressible | partially by BacA\p35^UAS.cHa, Scer\GAL4^Tub.PU

(Zielke et al., 2022)

Other

Statement

Reference

Myc^UAS.cZa, Scer\GAL4^Tub.PU, ppan^Ebox has wing disc | somatic clone | larval stage phenotype

(Zielke et al., 2022)

Ecol\lexA^GAD.UAS.cZa, Scer\GAL4^en.PU, ppan^Ebox has wing disc | somatic clone | larval stage phenotype

(Zielke et al., 2022)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

95522

w^*; P{neoFRT}82B TI{TI}ppan^Ebox

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Ppan^Ebox

(Zielke et al., 2022)

Ppan^LexO_A5

(Zielke et al., 2022)

ppan^Ebox

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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