FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Raf926
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General Information
Symbol
Dmel\Raf926
Species
D. melanogaster
Name
FlyBase ID
FBal0374655
Feature type
allele
Associated gene
Dmel\Raf
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Lusk et al., 2022)
Mutagen
ethyl methanesulfonate
(Lusk et al., 2022)
Progenitor genotype
Cytology
Description

17bp deletion beginning at the 479th nucleotide of the Raf protein coding region. This results in a frameshift, leading to a premature stop codon before the second and third conserved domains, as well as deleting the majority of the first conserved domain.

(Lusk et al., 2022)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
X:2,341,494..2,341,510 [+]
Comment:

A 17bp deletion beginning in codon 160 of Raf causes a frameshift and leads to early translation termination.

(Lusk et al., 2022)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Raf926
      (Lusk et al., 2022)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)