FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\nordΔ1728
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General Information
Symbol
Dmel\nordΔ1728
Species
D. melanogaster
Name
FlyBase ID
FBal0375941
Feature type
allele
Associated gene
Dmel\nord
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Akiyama et al., 2022)
Mutagen
CRISPR/Cas9
(Akiyama et al., 2022)
Progenitor genotype
Cytology
Description

A 1728 bp deletion of the nord CDS, causing a frameshift and early termination codon, resulting in a predicted protein truncation lacking a large portions of the NDNF domain (which is essential for its function).

(Akiyama et al., 2022)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
2R:24,252,681..24,252,681 [+]
Comment:

A 1728 bp deletion within the nord CDS, leading to a frameshift and early translation termination.

(Akiyama and Gibson, 2022.9.6)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      nordΔ1728/nordΔ1728 is an enhancer of visible | adult stage phenotype of dallygem

      (Akiyama et al., 2022)

      nordΔ1728/nordΔ1728 is an enhancer of decreased size | adult stage phenotype of dallygem

      (Akiyama et al., 2022)
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      nordΔ1728 has posterior crossvein | ectopic phenotype, enhanceable by tkv8/tkv[+]

      (Akiyama et al., 2022)

      nordΔ1728 has posterior crossvein | ectopic phenotype, enhanceable by Mad12/Mad[+]

      (Akiyama et al., 2022)
      Enhancer of
      Statement
      Reference

      nordΔ1728/nordΔ1728 is an enhancer of wing phenotype of dallygem

      (Akiyama et al., 2022)
      Suppressor of
      Statement
      Reference

      nord[+]/nordΔ1728 is a suppressor | partially of wing vein L5 phenotype of dallygem

      (Akiyama et al., 2022)

      nordΔ1728/nordΔ1728 is a suppressor of wing vein L5 phenotype of dallygem

      (Akiyama et al., 2022)
      Other
      Statement
      Reference

      dallygem, nordΔ1728 has gonad | male | larval stage phenotype

      (Akiyama et al., 2022)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      nordΔ1728
      (Akiyama et al., 2022)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)