FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Ir94elexA
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General Information
Symbol
Dmel\Ir94elexA
Species
D. melanogaster
Name
FlyBase ID
FBal0376356
Feature type
allele
Associated gene
Dmel\Ir94e
Associated Insertion(s)
TI{lexA::p65}Ir94elexA
Carried in Construct
Key Links
Genomic Maps

Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(McDowell et al., 2022)
Mutagen
CRISPR/Cas9
(McDowell et al., 2022)
gene targeting by homologous recombination
(McDowell et al., 2022)
Progenitor genotype
Associated Insertion(s)
TI{lexA::p65}Ir94elexA
Cytology
Description

Most of the coding sequence (1843bp deletion) of Ir94e has been replaced with a cassette containing lexA::p65-Tag:NLS(Unk) and a Disc\RFP3xP3.cUa marker, flanked by loxP sites.

(McDowell et al., 2022)
Allele components
Component
Use(s)
Inserted element
TI{lexA::p65}
Encoded product / tool
lexA::p65
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
delins
3R:23,405,509..23,407,351 [+]
Comment:

Most of the coding sequence (1843bp deletion) of Ir94e has been replaced with a cassette containing lexA::p65-Tag:NLS(Unk) and a Disc\RFP3xP3.cUa marker, flanked by loxP sites. The Ir94e deletion extends from the ATG start codon to -49 relative to the stop codon.

(McDowell et al., 2022)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      IR94eLexA
      (Guillemin et al., 2025, Guillemin et al., 2024)
      IR94eLexARFP
      (Li et al., 2025)
      Ir94elexA
      Name Synonyms
      Secondary FlyBase IDs
        References (4)