FlyBase Allele Report: Dmel\Tom40[UAS.Tag:FLAG,Tag:HA]

General Information

Symbol

Dmel\Tom40^{UAS.Tag:FLAG,Tag:HA}

Species

D. melanogaster

Name

FlyBase ID

FBal0386963

Feature type

allele

Associated gene

Dmel\Tom40

Associated Insertion(s)

Carried in Construct

P{UAS-Tom40.FLAG.HA}

Key Links

Transgenic product class

wild_type

(Periasamy et al., 2022)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Periasamy et al., 2022)

Mutagen

in vitro construct

(Periasamy et al., 2022)

Progenitor genotype

Carried in construct

P{UAS-Tom40.FLAG.HA}

Cytology

Description

UAS regulatory sequences drive expression of Tom40 that is tagged with Tag:FLAG and Tag:HA.

(Periasamy et al., 2022)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Tagged with

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 1 )

Disease

Evidence

References

model of Alzheimer's disease

CEA

(Periasamy et al., 2022)

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

model of Alzheimer's disease

is ameliorated by BacA\p35^UAS.cHa

(Periasamy et al., 2022)

is ameliorated by Diap1^UAS.cHa

(Periasamy et al., 2022)

is ameliorated by Tom20^HMC05788

(Periasamy et al., 2022)

is ameliorated by Tom7^HMC06597

(Periasamy et al., 2022)

is ameliorated by mge^KK108018

(Periasamy et al., 2022)

is exacerbated by mge^{UAS.Tag:FLAG,Tag:HA}

(Periasamy et al., 2022)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal eye color, with Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

decreased size | adult stage, with Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

increased cell death | larval stage, with Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

visible | adult stage, with Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

Phenotype Manifest In

eye, with Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

eye disc | larval stage, with Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

ommatidium, with Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^GMR.PFa, Tom40^{UAS.Tag:FLAG,Tag:HA} has visible | adult stage phenotype, enhanceable by mge^{UAS.Tag:FLAG,Tag:HA}/Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

NOT Enhanced by

Statement

Reference

Scer\GAL4^GMR.PFa, Tom40^{UAS.Tag:FLAG,Tag:HA} has visible | adult stage phenotype, non-enhanceable by Buffy^JF03287, Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

Scer\GAL4^GMR.PFa, Tom40^{UAS.Tag:FLAG,Tag:HA} has visible | adult stage phenotype, non-enhanceable by Tim23^HMC06553/Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

Scer\GAL4^GMR.PFa, Tom40^{UAS.Tag:FLAG,Tag:HA} has visible | adult stage phenotype, non-enhanceable by sesB^JF01528/Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

Scer\GAL4^GMR.PFa, Tom40^{UAS.Tag:FLAG,Tag:HA} has visible | adult stage phenotype, non-enhanceable by porin^JF03251/Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

Scer\GAL4^GMR.PFa, Tom40^{UAS.Tag:FLAG,Tag:HA} has visible | adult stage phenotype, non-enhanceable by Buffy^UAS.cQa, Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

Scer\GAL4^GMR.PFa, Tom40^{UAS.Tag:FLAG,Tag:HA} has visible | adult stage phenotype, non-enhanceable by Debcl^JF02429, Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

Scer\GAL4^GMR.PFa, Tom40^{UAS.Tag:FLAG,Tag:HA} has visible | adult stage phenotype, non-enhanceable by Tim9b^{UAS.Tag:Rho1D4}/Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

Suppressed by

Statement

Reference

Scer\GAL4^GMR.PFa, Tom40^{UAS.Tag:FLAG,Tag:HA} has visible | adult stage phenotype, suppressible by BacA\p35^UAS.cHa, Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

Scer\GAL4^GMR.PFa, Tom40^{UAS.Tag:FLAG,Tag:HA} has visible | adult stage phenotype, suppressible by Diap1^UAS.cHa, Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

Scer\GAL4^GMR.PFa, Tom40^{UAS.Tag:FLAG,Tag:HA} has visible | adult stage phenotype, suppressible by mge^KK108018/Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

Scer\GAL4^GMR.PFa, Tom40^{UAS.Tag:FLAG,Tag:HA} has visible | adult stage phenotype, suppressible by Tom20^HMC05788/Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

Scer\GAL4^GMR.PFa, Tom40^{UAS.Tag:FLAG,Tag:HA} has visible | adult stage phenotype, suppressible by Tom7^HMC06597/Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

NOT suppressed by

Statement

Reference

Scer\GAL4^GMR.PFa, Tom40^{UAS.Tag:FLAG,Tag:HA} has visible | adult stage phenotype, non-suppressible by porin^JF03251/Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

Scer\GAL4^GMR.PFa, Tom40^{UAS.Tag:FLAG,Tag:HA} has visible | adult stage phenotype, non-suppressible by sesB^JF01528/Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

Scer\GAL4^GMR.PFa, Tom40^{UAS.Tag:FLAG,Tag:HA} has visible | adult stage phenotype, non-suppressible by Tim23^HMC06553/Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

Scer\GAL4^GMR.PFa, Tom40^{UAS.Tag:FLAG,Tag:HA} has visible | adult stage phenotype, non-suppressible by Tim9b^{UAS.Tag:Rho1D4}/Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

Scer\GAL4^GMR.PFa, Tom40^{UAS.Tag:FLAG,Tag:HA} has visible | adult stage phenotype, non-suppressible by Buffy^JF03287, Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

Scer\GAL4^GMR.PFa, Tom40^{UAS.Tag:FLAG,Tag:HA} has visible | adult stage phenotype, non-suppressible by Debcl^JF02429, Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

Scer\GAL4^GMR.PFa, Tom40^{UAS.Tag:FLAG,Tag:HA} has visible | adult stage phenotype, non-suppressible by Buffy^UAS.cQa, Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

Phenotype Manifest In

Enhanced by

Statement

Reference

Scer\GAL4^GMR.PFa, Tom40^{UAS.Tag:FLAG,Tag:HA} has eye phenotype, enhanceable by mge^{UAS.Tag:FLAG,Tag:HA}/Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

NOT Enhanced by

Statement

Reference

Scer\GAL4^GMR.PFa, Tom40^{UAS.Tag:FLAG,Tag:HA} has eye phenotype, non-enhanceable by Buffy^JF03287, Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

Scer\GAL4^GMR.PFa, Tom40^{UAS.Tag:FLAG,Tag:HA} has eye phenotype, non-enhanceable by Tim23^HMC06553/Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

Scer\GAL4^GMR.PFa, Tom40^{UAS.Tag:FLAG,Tag:HA} has eye phenotype, non-enhanceable by sesB^JF01528/Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

Scer\GAL4^GMR.PFa, Tom40^{UAS.Tag:FLAG,Tag:HA} has eye phenotype, non-enhanceable by porin^JF03251/Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

Scer\GAL4^GMR.PFa, Tom40^{UAS.Tag:FLAG,Tag:HA} has eye phenotype, non-enhanceable by Buffy^UAS.cQa, Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

Scer\GAL4^GMR.PFa, Tom40^{UAS.Tag:FLAG,Tag:HA} has eye phenotype, non-enhanceable by Debcl^JF02429, Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

Scer\GAL4^GMR.PFa, Tom40^{UAS.Tag:FLAG,Tag:HA} has eye phenotype, non-enhanceable by Tim9b^{UAS.Tag:Rho1D4}/Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

Suppressed by

Statement

Reference

Scer\GAL4^GMR.PFa, Tom40^{UAS.Tag:FLAG,Tag:HA} has eye phenotype, suppressible by Diap1^UAS.cHa, Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

Scer\GAL4^GMR.PFa, Tom40^{UAS.Tag:FLAG,Tag:HA} has eye phenotype, suppressible by mge^KK108018/Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

Scer\GAL4^GMR.PFa, Tom40^{UAS.Tag:FLAG,Tag:HA} has eye phenotype, suppressible by Tom7^HMC06597/Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

Scer\GAL4^GMR.PFa, Tom40^{UAS.Tag:FLAG,Tag:HA} has eye phenotype, suppressible by Tom20^HMC05788/Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

Scer\GAL4^GMR.PFa, Tom40^{UAS.Tag:FLAG,Tag:HA} has eye phenotype, suppressible by BacA\p35^UAS.cHa, Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

NOT suppressed by

Statement

Reference

Scer\GAL4^GMR.PFa, Tom40^{UAS.Tag:FLAG,Tag:HA} has eye phenotype, non-suppressible by Buffy^JF03287, Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

Scer\GAL4^GMR.PFa, Tom40^{UAS.Tag:FLAG,Tag:HA} has eye phenotype, non-suppressible by Buffy^UAS.cQa, Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

Scer\GAL4^GMR.PFa, Tom40^{UAS.Tag:FLAG,Tag:HA} has eye phenotype, non-suppressible by Debcl^JF02429, Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

Scer\GAL4^GMR.PFa, Tom40^{UAS.Tag:FLAG,Tag:HA} has eye phenotype, non-suppressible by Tim9b^{UAS.Tag:Rho1D4}/Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

Scer\GAL4^GMR.PFa, Tom40^{UAS.Tag:FLAG,Tag:HA} has eye phenotype, non-suppressible by Tim23^HMC06553/Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

Scer\GAL4^GMR.PFa, Tom40^{UAS.Tag:FLAG,Tag:HA} has eye phenotype, non-suppressible by sesB^JF01528/Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

Scer\GAL4^GMR.PFa, Tom40^{UAS.Tag:FLAG,Tag:HA} has eye phenotype, non-suppressible by porin^JF03251/Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

Tom40^{UAS.Tag:FLAG,Tag:HA} is rescued by Tom40^JF02030/Scer\GAL4^GMR.PFa

(Periasamy et al., 2022)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Tom40^{UAS.Tag:FLAG,Tag:HA}

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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