FlyBase Allele Report: Hsap\IGF2BP1[UAS.cFa]

FB2026_01 , released March 12, 2026

FB2026_01 , released March 12, 2026

Allele: Hsap\IGF2BP1^UAS.cFa

General Information

Symbol

Hsap\IGF2BP1^UAS.cFa

Species

H. sapiens

Name

UAS construct a of Fujino

FlyBase ID

FBal0392835

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

P{UAS-hIGF2BP1.F}

Also Known As

UAS-IGF2BP1

Key Links

Transgenic product class

(Fujino et al., 2023)

(Fujino et al., 2023)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

(Fujino et al., 2023)

(Fujino et al., 2023)

Mutagen

in vitro construct

(Fujino et al., 2023)

Progenitor genotype

Carried in construct

P{UAS-hIGF2BP1.F}

Cytology

Description

UASt regulatory sequences drive expression of wild-type Hsap\IGF2BP1 cDNA (NM_006546.4).

(Fujino et al., 2023)

Allele components

Component

Use(s)

Regulatory region(s)

binary expression system - regulatory region

Encoded product / tool

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates C9orf72 frontotemporal dementia and/or amyotrophic lateral sclerosis

modeled by Zzzz\GGGGCC^42.UAS

(Fujino et al., 2023)

modeled by Zzzz\GGGGCC^89.UAS

(Fujino et al., 2023, Taminato et al., 2023)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Hsap\IGF2BP1^UAS.cFa, Scer\GAL4^GMR.PS is a suppressor of abnormal eye color phenotype of Scer\GAL4^GMR.PS, Zzzz\GGGGCC^42.UAS

(Fujino et al., 2023)

Hsap\IGF2BP1^UAS.cFa, Scer\GAL4^GMR.PS is a suppressor of decreased size | adult stage phenotype of Scer\GAL4^GMR.PS, Zzzz\GGGGCC^89.UAS

(Fujino et al., 2023)

Hsap\IGF2BP1^UAS.cFa, Scer\GAL4^GMR.PS is a suppressor of abnormal eye color phenotype of Scer\GAL4^GMR.PS, Zzzz\GGGGCC^89.UAS

(Fujino et al., 2023)

Phenotype Manifest In

Suppressor of

Statement

Reference

Hsap\IGF2BP1^UAS.cFa, Scer\GAL4^GMR.PS is a suppressor of eye phenotype of Scer\GAL4^GMR.PS, Zzzz\GGGGCC^42.UAS

(Fujino et al., 2023)

Hsap\IGF2BP1^UAS.cFa, Scer\GAL4^GMR.PS is a suppressor of eye phenotype of Scer\GAL4^GMR.PS, Zzzz\GGGGCC^89.UAS

(Fujino et al., 2023)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Hsap\IGF2BP1^UAS.cFa

Name Synonyms

UAS construct a of Fujino

Secondary FlyBase IDs

References (2)

Report Sections