FlyBase Allele Report: Dmel\Arlr[262]

General Information

Symbol

Dmel\Arlr²⁶²

Species

D. melanogaster

Name

FlyBase ID

FBal0396714

Feature type

allele

Associated gene

Dmel\Arlr

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

amorphic allele - molecular evidence

Mutagen

CRISPR/Cas9

Nature of the Allele

Allele class

amorphic allele - molecular evidence

(Sun et al., 2023)

Mutagen

CRISPR/Cas9

(Sun et al., 2023)

Progenitor genotype

Cytology

Description

Deletion of 1261-1523 bp in the coding sequence.

(Sun et al., 2023)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

deletion

X:10,928,982..10,929,244 [+]

Comment:

Deletion of 1261-1523 bp in the Arlr CDS.

(Sun et al., 2023)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal starvation stress response | adult stage

(Sun et al., 2023)

decreased size | adult stage | progressive

(Sun et al., 2023)

increased size | adult stage, with Arlr^{ΔSP.UAS.Tag:HA}, Scer\GAL4^ppl.PP

(Sun et al., 2023)

short lived

(Sun et al., 2023)

viable

(Sun et al., 2023)

Phenotype Manifest In

lipid droplet | adult stage, with Arlr^{ΔSP.UAS.Tag:HA}, Scer\GAL4^ppl.PP

(Sun et al., 2023)

lipid droplet | adult stage | increased number

(Sun et al., 2023)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Arlr²⁶² has decreased size | adult stage | progressive phenotype, suppressible by Lsd1^TH04820.N/Scer\GAL4^ppl.PP

(Sun et al., 2023)

Arlr²⁶² has decreased size | adult stage | progressive phenotype, suppressible by Scer\GAL4^ppl.PP/regucalcin^HMS01598

(Sun et al., 2023)

Arlr²⁶² has decreased size | adult stage | progressive phenotype, suppressible by Hsap\ENDOU^UAS.Tag:HA/Scer\GAL4^ppl.PP

(Sun et al., 2023)

Arlr²⁶² has decreased size | adult stage | progressive phenotype, suppressible by Acaa^THU3344/Scer\GAL4^ppl.PP

(Sun et al., 2023)

Arlr²⁶² has decreased size | adult stage | progressive phenotype, suppressible by Scer\GAL4^ppl.PP/CG5162^TH03231.N

(Sun et al., 2023)

Arlr²⁶² has decreased size | adult stage | progressive phenotype, suppressible by Scer\GAL4^ppl.PP/EndoU^UAS.Tag:HA

(Sun et al., 2023)

Phenotype Manifest In

Suppressed by

Statement

Reference

Arlr²⁶² has lipid droplet | increased number | adult stage phenotype, suppressible by Hsap\ENDOU^UAS.Tag:HA/Scer\GAL4^ppl.PP

(Sun et al., 2023)

Arlr²⁶² has lipid droplet | increased number | adult stage phenotype, suppressible by Lsd1^TH04820.N/Scer\GAL4^ppl.PP

(Sun et al., 2023)

Arlr²⁶² has lipid droplet | increased number | adult stage phenotype, suppressible by Scer\GAL4^ppl.PP/regucalcin^HMS01598

(Sun et al., 2023)

Arlr²⁶² has lipid droplet | increased number | adult stage phenotype, suppressible by Scer\GAL4^ppl.PP/CG5162^TH03231.N

(Sun et al., 2023)

Arlr²⁶² has lipid droplet | increased number | adult stage phenotype, suppressible by Acaa^THU3344/Scer\GAL4^ppl.PP

(Sun et al., 2023)

Arlr²⁶² has lipid droplet | increased number | adult stage phenotype, suppressible by Scer\GAL4^ppl.PP/EndoU^UAS.Tag:HA

(Sun et al., 2023)

NOT Enhancer of

Statement

Reference

Arlr²⁶² is a non-enhancer of lipid droplet | adult stage | decreased number phenotype of EndoU^GD3933, Scer\GAL4^ppl.PP

(Sun et al., 2023)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

Arlr²⁶² is rescued by Arlr^UAS.Tag:HA/Scer\GAL4^ppl.PP

(Sun et al., 2023)

Not rescued by

Arlr²⁶² is not rescued by Arlr^N.UAS.Tag:HA/Scer\GAL4^ppl.PP

(Sun et al., 2023)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Arlr²⁶²

arlr²⁶²

(Sun et al., 2023)

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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