FlyBase Allele Report: Hsap\FUNDC1[UAS.Tag:MYC]

General Information

Symbol

Hsap\FUNDC1^UAS.Tag:MYC

Species

H. sapiens

Name

FlyBase ID

FBal0397997

Feature type

allele

Associated gene

Hsap\FUNDC1

Associated Insertion(s)

Carried in Construct

P{UAS-hFUNDC1.WT.MYC}

Key Links

Transgenic product class

wild_type

(Xu et al., 2023)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Xu et al., 2023)

Mutagen

in vitro construct

(Xu et al., 2023)

Progenitor genotype

Carried in construct

P{UAS-hFUNDC1.WT.MYC}

Cytology

Description

UAS regulates expression of wild type Hsap\FUNDC1 tagged with Tag:MYC.

(Xu et al., 2023)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Hsap\FUNDC1

Tagged with

Tag:MYC

epitope tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates Parkinson's disease 6

modeled by Pink1^B9

(Xu et al., 2023)

modeled by Pink1^RNAi.UAS.cYa

(Xu et al., 2023)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

Scer\GAL4^Mhc.PU, Hsap\FUNDC1^UAS.Tag:MYC is a non-enhancer of visible | adult stage phenotype of Drp1^TH02258.N, Pink1^RNAi.UAS.cYa, Scer\GAL4^Mhc.PU

(Xu et al., 2023)

Suppressor of

Statement

Reference

Hsap\FUNDC1^UAS.Tag:MYC, Scer\GAL4^Mhc.PU is a suppressor of visible | adult stage phenotype of Pink1^RNAi.UAS.cYa, Scer\GAL4^Mhc.PU

(Xu et al., 2023)

Hsap\FUNDC1^UAS.Tag:MYC, Scer\GAL4^Mhc.PU is a suppressor of decreased rate of adult locomotory behavior phenotype of Pink1^RNAi.UAS.cYa, Scer\GAL4^Mhc.PU

(Xu et al., 2023)

Hsap\FUNDC1^UAS.Tag:MYC/Scer\GAL4^Mhc.PU is a suppressor of increased cell death | adult stage phenotype of Pink1^B9

(Xu et al., 2023)

Hsap\FUNDC1^UAS.Tag:MYC/Scer\GAL4^Mhc.PU is a suppressor of visible | adult stage phenotype of Pink1^B9

(Xu et al., 2023)

NOT Suppressor of

Statement

Reference

Scer\GAL4^Mhc.PU, Hsap\FUNDC1^UAS.Tag:MYC is a non-suppressor of visible | adult stage phenotype of Drp1^TH02258.N, Pink1^RNAi.UAS.cYa, Scer\GAL4^Mhc.PU

(Xu et al., 2023)

Phenotype Manifest In

NOT Enhancer of

Statement

Reference

Scer\GAL4^Mhc.PU, Hsap\FUNDC1^UAS.Tag:MYC is a non-enhancer of wing phenotype of Drp1^TH02258.N, Pink1^RNAi.UAS.cYa, Scer\GAL4^Mhc.PU

(Xu et al., 2023)

Suppressor of

Statement

Reference

Hsap\FUNDC1^UAS.Tag:MYC, Scer\GAL4^Mhc.PU is a suppressor of adult thorax phenotype of Pink1^RNAi.UAS.cYa, Scer\GAL4^Mhc.PU

(Xu et al., 2023)

Hsap\FUNDC1^UAS.Tag:MYC, Scer\GAL4^Mhc.PU is a suppressor of indirect flight muscle phenotype of Pink1^RNAi.UAS.cYa, Scer\GAL4^Mhc.PU

(Xu et al., 2023)

Hsap\FUNDC1^UAS.Tag:MYC, Scer\GAL4^Mhc.PU is a suppressor of mitochondrion | adult stage phenotype of Pink1^RNAi.UAS.cYa, Scer\GAL4^Mhc.PU

(Xu et al., 2023)

Hsap\FUNDC1^UAS.Tag:MYC, Scer\GAL4^ple.PU is a suppressor of mitochondrion phenotype of Pink1^RNAi.UAS.cYa, Scer\GAL4^ple.PU

(Xu et al., 2023)

Hsap\FUNDC1^UAS.Tag:MYC, Scer\GAL4^Mhc.PU is a suppressor of mitochondrial crista phenotype of Pink1^RNAi.UAS.cYa, Scer\GAL4^Mhc.PU

(Xu et al., 2023)

Hsap\FUNDC1^UAS.Tag:MYC, Scer\GAL4^Mhc.PU is a suppressor of indirect flight muscle phenotype of Fundc1^GD13307, Scer\GAL4^Mhc.PU

(Xu et al., 2023)

Hsap\FUNDC1^UAS.Tag:MYC, Scer\GAL4^Mhc.PU is a suppressor of mitochondrion | adult stage phenotype of Fundc1^GD13307, Scer\GAL4^Mhc.PU

(Xu et al., 2023)

Hsap\FUNDC1^UAS.Tag:MYC/Scer\GAL4^Mhc.PU is a suppressor of indirect flight muscle phenotype of Pink1^B9

(Xu et al., 2023)

Hsap\FUNDC1^UAS.Tag:MYC/Scer\GAL4^Mhc.PU is a suppressor of wing phenotype of Pink1^B9

(Xu et al., 2023)

Hsap\FUNDC1^UAS.Tag:MYC/Scer\GAL4^Mhc.PU is a suppressor of adult thorax phenotype of Pink1^B9

(Xu et al., 2023)

Hsap\FUNDC1^UAS.Tag:MYC, Scer\GAL4^Mhc.PU is a suppressor of wing phenotype of Pink1^RNAi.UAS.cYa, Scer\GAL4^Mhc.PU

(Xu et al., 2023)

NOT Suppressor of

Statement

Reference

Scer\GAL4^Mhc.PU, Hsap\FUNDC1^UAS.Tag:MYC is a non-suppressor of wing phenotype of Drp1^TH02258.N, Pink1^RNAi.UAS.cYa, Scer\GAL4^Mhc.PU

(Xu et al., 2023)

Scer\GAL4^Mhc.PU, Hsap\FUNDC1^UAS.Tag:MYC is a non-suppressor of indirect flight muscle phenotype of Drp1^TH02258.N, Pink1^RNAi.UAS.cYa, Scer\GAL4^Mhc.PU

(Xu et al., 2023)

Scer\GAL4^Mhc.PU, Hsap\FUNDC1^UAS.Tag:MYC is a non-suppressor of mitochondrion | adult stage phenotype of Drp1^TH02258.N, Pink1^RNAi.UAS.cYa, Scer\GAL4^Mhc.PU

(Xu et al., 2023)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Hsap\FUNDC1^UAS.Tag:MYC

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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