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General Information
Symbol
Scer\GAL4ple.PU
Species
S. cerevisiae
Name
pale promoter construct of Unknown
FlyBase ID
FBal0298778
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
TH-Gal4
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

GAL4 expression is driven by ple promoter sequences.

Allele components
Product class / Tool use(s)
Regulatory region(s)
Expression Data
Reporter Expression
distribution deduced from reporter (Gal4 UAS)
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Inhibition (using shi1.UAS at 32[o]C) of Scer\GAL4ple.PU cells in adults during training blocks the increase in aversive olfactory 24 h memory observed when the recall environment better matches the training environment (presence of copper grid), compared to controls.

Activation of neurons expressing Scer\GAL4ple.PU through overexpression of temperature sensitive TrpA1 results in increased sleep loss in both young (1 day) and mature (7-8 day) flies compared to controls. The effects are similar in males and females and independent of day and night. No gross changes in dopamine cell anatomy are observed. When these neurons are activated for three days from day one after eclosion exhibit a reduced courtship index and severe reduction in copulation frequency at day 5. No effect on courtship is seen at day 12 when the neurons are activated for three days from day 7. The flies that are sleep-deprived when young, but not those sleep-deprived when mature, show a reduction in size of the VA1v fru[+] glomerulus caused by impaired post-eclosion growth. The volumes of the DA1, DL3 and VA1d glomeruli are unaffected.

Silencing of neurons expressing Scer\GAL4ple.PU through overexpression of shi results in significantly increased sleep in mature (7-8 day) flies compared to controls. A milder increase in sleep is seen in young (1 day old) flies).

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Suppressed by
Statement
Reference
NOT suppressed by
Statement
Reference
Enhancer of
Suppressor of
Statement
Reference
Phenotype Manifest In
Enhanced by
Suppressed by
Statement
Reference
NOT suppressed by
Enhancer of
Statement
Reference
Suppressor of
Statement
Reference

Scer\GAL4ple.PU is a suppressor of mitochondrion phenotype of Pink1B9

Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Scer\GAL4ple.PU
Name Synonyms
pale promoter construct of Unknown
Secondary FlyBase IDs
    References (43)