FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\TrxTKO
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General Information
Symbol
Dmel\TrxTKO
Species
D. melanogaster
Name
FlyBase ID
FBal0404618
Feature type
allele
Associated gene
Dmel\TrxT
Associated Insertion(s)
TI{TI}TrxTKO
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
CRISPR/Cas9
(Molnar et al., 2024)
gene targeting by homologous recombination
(Molnar et al., 2024)
Progenitor genotype
Associated Insertion(s)
TI{TI}TrxTKO
Cytology
Description

The entire TrxT coding sequence has been deleted and replaced with sequence that encodes 1. an attP site, and 2. a loxP cassette containing a Disc\RFPDsRed.3xP3.cUa marker.

(Molnar et al., 2024)
Allele components
Component
Use(s)
Also carries
attP
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      TrxTKO is a suppressor | partially of abnormal size | larval stage phenotype of l(3)mbtts1

      (Molnar et al., 2024)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      TrxTKO is a suppressor | partially of larval inner optic anlage phenotype of l(3)mbtts1

      (Molnar et al., 2024)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      TrxTKO
      (Molnar et al., 2024)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)